Posts about medical study

Diet May Help ADHD Kids More Than Drugs

Diet May Help ADHD Kids More Than Drugs

Kids with ADHD can be restless and difficult to handle. Many of them are treated with drugs, but a new study says food may be the key. Published in The Lancet journal, the study suggests that with a very restrictive diet, kids with ADHD could experience a significant reduction in symptoms.

The study’s lead author, Dr. Lidy Pelsser of the ADHD Research Centre in the Netherlands, writes in The Lancet that the disorder is triggered in many cases by external factors — and those can be treated through changes to one’s environment. “ADHD, it’s just a couple of symptoms — it’s not a disease,” the Dutch researcher tells All Things Considered weekend host Guy Raz.

The way we think about — and treat — these behaviors is wrong, Pelsser says. “There is a paradigm shift needed. If a child is diagnosed ADHD, we should say, ‘OK, we have got those symptoms, now let’s start looking for a cause.’ ”

According to Pelsser, 64 percent of children diagnosed with ADHD are actually experiencing a hypersensitivity to food. Researchers determined that by starting kids on a very elaborate diet, then restricting it over a few weeks’ time. “It’s only five weeks,” Pelsser says. “If it is the diet, then we start to find out which foods are causing the problems.”

Teachers and doctors who worked with children in the study reported marked changes in behavior. “In fact, they were flabbergasted,” Pelsser says.

Related: Nearly 1 million Children Potentially Misdiagnosed with ADHD in the USALifestyle Drugs and RiskOver-reliance on Prescription Drugs to Aid Children’s Sleep?Epidemic of Diagnoses
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Aerobic Exercise Plus Resistance Training Helps Control Type 2 Diabetes

Exercise Combo Best for Controlling Diabetes

A combination of aerobic exercise and resistance training may offer the biggest benefits for people with type 2 diabetes in helping them control their disease.

HbA1c is a test that measures blood sugar control for the previous few months. Normal HbA1c is 6% or less. People with diabetes are urged to keep their HbA1c below 7%.

In the study, researchers compared the effects of a nine-month aerobic exercise program, a resistance training program, and combination exercise program vs. not exercising in 262 previously sedentary men and women with type 2 diabetes. The results showed that improvements in HbA1c levels were greatest among those who were in the combination group.

Thirty-nine percent of non-exercisers had to increase these medications compared with 32% in the resistance training group, 22% in the aerobic exercise group, and 18% in the combination group.

Diabetes is a huge and growing problem. Exercise is a good strategy to remain healthy. It is best to exercise and avoid becoming sick. But if you do get diabetes then it is even more important to take care to exercise properly.

Related: Surprising New Diabetes DataDiabetes up 90% in USA since 1997 – Study Finds Obesity as Teen as Deadly as Smoking

Being sociable is good for your health

With a little help from your friends you can live longer

A circle of close friends and strong family ties can boost a person’s health more than exercise, losing weight or quitting cigarettes and alcohol, psychologists say.

Holt-Lunstad’s team reviewed 148 studies that tracked the social interactions and health of 308,849 people over an average of 7.5 years. From these they worked out how death rates varied depending on how sociable a person was.

Being lonely and isolated was as bad for a person’s health as smoking 15 cigarettes a day or being an alcoholic. It was as harmful as not exercising and twice as bad for the health as being obese.

Open access paper: Social Relationships and Mortality Risk: A Meta-analytic Review.

Related: How to build and maintain essential relationshipsCDC Urges Reduction in Salt Intake to Save Hundreds of Thousands of LivesWhy People Often Get Sicker When They’re Stressed

CDC Urges Reduction in Salt Intake to Save Hundreds of Thousands of Lives

Most people know we eat far too much salt and that it is killing lots of us. It is soft of crazy though that we have over 100,000 people in the USA every year die this way and yet we barely pay attention. Doesn’t it seem like we should care more about life?

Excessive dietary sodium consumption increases blood pressure, which increases the risk for stroke, coronary heart disease, heart failure, and renal disease. Based on predictive modeling of the health benefits of reduced salt intake on blood pressure, a population-wide reduction in sodium of 1,200 mg/day would reduce the annual number of new cases of coronary heart disease by 60,000—120,000 cases and stroke by 32,000—66,000 cases.

Fewer than 10% of all adults in the USA met their recommended limit. U.S. adults consumed an average of 3,466 mg/day of sodium. Most of the daily sodium consumed came from grains (1,288 mg; 36.9%) and meats, poultry, fish, and mixtures (994 mg; 27.9%).

In the United States, an estimated 77% of dietary sodium intake comes from processed and restaurant foods and approximately 10% comes from table salt and cooking. More details from the CDC.

Related: CDC: Reduce Salt in Your DietFood Rules: An Eater’s ManualEat Less Salt and Save Your HeartAnother Strike Against Cola

Smokers with High Blood Pressure and High Cholesterol Lose 10 Years

By examining data from the Whitehall Study researchers have found smokers with high blood pressure and high cholesterol in middle age died 10 years earlier than the others after reaching age 50. This is independent of changes after later in life (quiting smoking, etc.). Life expectancy in relation to cardiovascular risk factors: 38 year follow-up of 19,000 men in the Whitehall study

At entry, 42% of the men were current smokers, 39% had high blood pressure, and 51% had high cholesterol. At the re-examination, about two thirds of the previously “current” smokers had quit smoking shortly after entry and the mean differences in levels of those with high and low levels of blood pressure and cholesterol were attenuated by two thirds. Compared with men without any baseline risk factors, the presence of all three risk factors at entry was associated with a 10 year shorter life expectancy from age 50 (23.7 v 33.3 years). Compared with men in the lowest 5% of a risk score based on smoking, diabetes, employment grade, and continuous levels of blood pressure, cholesterol concentration, and body mass index (BMI), men in the highest 5% had a 15 year shorter life expectancy from age 50 (20.2 v 35.4 years).

Conclusion Despite substantial changes in these risk factors over time, baseline differences in risk factors were associated with 10 to 15 year shorter life expectancy from age 50.

Another conclusion: if you don’t want to live a shorter life, don’t smoke. Not a new idea but given how many people continue to smoke it seems some don’t understand this conclusion.

Related: Global Cancer Deaths to Double by 2030Leading Causes of Deathmore posts on open access papersStudy Finds Obesity as Teen as Deadly as Smoking

Merck and Elsevier Publish Phony Peer-Review Journal

Elsevier is one of those publishers fighting open science. They try to claim that the government publishing government funded research in an open way will tarnish science. The argument makes no sense to me. Here is another crazy action on their part: they published a “journal” funded by Merck to promote Merck products. Merck Makes Phony Peer-Review Journal:

Merck cooked up a phony, but real sounding, peer reviewed journal and published favorably looking data for its products in them. Merck paid Elsevier to publish such a tome, which neither appears in MEDLINE or has a website, according to The Scientist.

What’s sad is that I’m sure many a primary care physician was given literature from Merck that said, “As published in Australasian Journal of Bone and Joint Medicine, Fosamax outperforms all other medications….” Said doctor, or even the average researcher wouldn’t know that the journal is bogus. In fact, knowing that the journal is published by Elsevier gives it credibility!

As I have said the journals fighting open science should have their credibility questioned. They are putting their outdated business model above science. We should not see organizations that are focused on closing science research through deceptive publicity efforts and lobbying efforts as credible.

Related: From Ghost Writing to Ghost Management in Medical JournalsMerck Faked a Research JournalMedical Study Integrity (or Lack Thereof)The Future of Scholarly PublicationFresh questions raised about prominent cardiologist’s role in “ghostwritten” 2001 meta-analysis of Vioxx trialsScience Commons: Making Scientific Research Re-usefulPublishers Continue to Fight Open Access to ScienceMisleading or Deceptive ConductPeter Suber Response to Rep. Conyers

Ozone Pollution Taking Toll on American Lives

Ozone Pollution Taking Toll on American Lives by Amanda Gardner

Thousands of Americans are dying each year from lung disease caused by atmospheric ozone, a new study finds.

The greatest risk may for those living be in hot, dry cities such as Los Angeles, which has one of the highest concentrations of ozone. Residents of Los Angeles may face a 25 percent to 30 percent higher annual risk of dying from a respiratory ailment versus people in low-ozone areas such as the Great Plains, the researchers said.

An estimated 240,000 people in the United States and 7.7 million people worldwide die of respiratory disease each year, according to data from the World Health Organization. Efforts to reduce ground-level ozone have stalled in recent years, Jarrett said, and now one in three Americans lives in an area that exceeds the national standard for ozone levels.

Ozone is also a powerful greenhouse gas, Jerrett said, so measures to improve health might have the added benefit of slowing climate change.

Related: Scientists Denounce Global Warming Report ‘Edits’Rate of Cancer Detected and Death Rates DeclinesThe Pollution Magnet

Study Shows Weight Loss From Calorie Reduction Not Low Fat or Low Carb

A Randomized Trial Comparing Low-Fat and Low-Carbohydrate Diets Matched for Energy and Protein

The preliminary results presented in this paper are for the first four of six postmenopausal overweight or obese participants who followed, in random order, both a VLC [very-low-carbohydrate] and an LF [low-fat] diet for 6 weeks. Other outcome measures were serum lipids, glucose, and insulin, as well as dietary compliance and side effects. Our results showed no significant weight loss, lipid, serum insulin, or glucose differences between the two diets. Lipids were dramatically reduced on both diets, with a trend for greater triglyceride reduction on the VLC diet. Glucose levels were also reduced on both diets, with a trend for insulin reduction on the VLC diet. Compliance was excellent with both diets, and side effects were mild

Essentially the study showed that the calories had an impact on weight loss but the makeup of those calories did not. Don’t forget this is just one study. Listen to interview with the Author, Frank Sacks, on Science Friday on NPR.

Related: Big Fat Lieposts on medical studiesWaste from Gut Bacteria Helps Control WeightCommon virus may contribute to obesity

Study Finds Obesity as Teen as Deadly as Smoking

A Swedish study has found obesity is as deadly (increasing adult mortality) as smoking for teens. Combined effects of overweight and smoking in late adolescence on subsequent mortality: nationwide cohort study

Regardless of smoking status, overweight and obesity in late adolescence increases the risk of adult mortality. Obesity and overweight were as hazardous as heavy and light smoking, respectively, but there was no interaction between BMI and smoking status. The global obesity epidemic and smoking among adolescents remain important targets for intensified public health initiatives.

Obesity Just as Risky for Teens as Heavy Smoking

Dr. Martin Neovius of the Karolinska Institute and colleagues analyzed data from more than 45,000 18-year-olds who underwent military conscription tests in which their body mass index (BMI) and smoking status were recorded. The men were followed for an average of 38 years.

During the follow-up period, 2,897 of the men died. The incidence of death was highest among obese men and lowest among those of normal weight. Compared with those who had a normal weight at age 18, those who had been overweight were about a third more likely to die early, whereas those who were obese were more than twice as likely to die prematurely.

Related: Global Cancer Deaths to Double by 2030Obesity Epidemic Partially Explained$500 Million to Reduce Childhood Obesity in USAActive Amish Avoid Obesity

Correlation is Not Causation: “Fat is Catching” Theory Exposed

“Fat is catching” theory exposed

Their study was reported to have shown that you can “catch” obesity from having fat friends and that obesity is so contagious, it can be spread long-distance by email and instant messaging. Even healthcare professionals, who didn’t understand the etiology of true obesity or how statistics can be misused, failed to detect the implausibility of “second-hand obesity.” In fact, some doctors became so enamored with the new “science of networking” they believed it should be a new medical specialty: network medicine.

Jason M. Fletcher, Ph.D., assistant professor at the Yale School of Public Health in New Haven, Connecticut, along with Boston economist, Ethan Cohen-Cole, Ph.D., designed an ingenious study. They selected conditions that no one would seriously believe were spread by social networking and online friendships: height, headaches and acne. They then applied the same standard statistical methods used in Christakis and Fowler’s social networking research to “find” that acne, height and headaches have the same “social network effect.”

As they explained, patterns of association among people can lead to correlations in health conditions between friends that are not caused by direct social network effects at all.

There is a need for caution when attributing causality to correlations in health outcomes between friends using non-experimental data. Confounding is only one of many empirical challenges to estimating social network effects.

Excellent reminder of the risks of analyzing data for correlations. We continue to, far to often, fail to interpret data properly. Both authors of the study, received PhD’s from the University of Wisconsin-Madison which strengthens my belief that it is teaching students well (just kidding).

Also another example of the scientific inquiry process where scientists challenge the conclusions drawn by other scientists. It is a wonderful system, even if confusing and not the clean idea so many have of how science works.

Related: Correlation is Not CausationSeeing Patterns Where None ExistsStatistics for Experimenters500 Year FloodsPlaying Dice and Children’s NumeracyThe Illusion of UnderstandingAll Models Are Wrong But Some Are UsefulData Doesn’t Lie But People Can Draw Faulty Conclusions from Data

Global Cancer Deaths to Double by 2030

Global Cancer Deaths to Double by 2030 by Salynn Boyles

Cancer deaths are projected to more than double worldwide over the next two decades, largely from a dramatic increase in cancer incidence in low- and middle-income countries driven by tobacco use and increasingly Westernized lifestyles.

A new report from the International Agency for Research on Cancer (IARC) explores the global burden of cancer, which is poised to become the leading cause of death worldwide by 2010. The report predicts that by 2030, 27 million new cancer cases and 17 million cancer deaths will occur each year worldwide. That compares to 12 million new cancers and slightly less than 8 million cancer deaths in 2007.

People really need to stop smoking. And we are pretty lame a society when we inflict such needless disease and death on our fellow humans. Curing millions of cancer patients 20 years from now will be very hard. but it isn’t hard to “cure” millions of them today. We just need people not to pay a lot of money to give themselves cancer by smoking.

Related: Nanospheres Targeting Cancer at MITRate of Cancer Detected and Death Rates Declines (in USA)Leading Causes of Death

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