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How patent gridlock is blocking the development of lifesaving drugs by Michael Heller, Forbes
This is a critical problem I have written about before. The broken patent system is a serious problem that needs to be fixed.
Related: The Effects of Patenting on Science - Patent Policy Harming USA, and the world - Patenting Life is a Bad Idea - The Differences Between Culture and Code - Innovation and Creative Commons - The Value of the Public Domain - The Patent System Needs to be Significantly Improved - Are Software Patents Evil?
A few weeks ago we posted about Tracking Down Tomato Troubles as another example of the challenges of scientific inquiry. Too often, in the rare instances that science is even discussed in the news, the presentation provides the illusion of simple obvious answers. Instead it is often a very confusing path until the answers are finally found (posts on scientific investigations in action). At which time it often seems obvious what was going on. But to get to the solutions we need dedicated and talented scientists to search for answers.
Now the CDC is saying tomatoes might not be the source of the salmonella after all: CDC investigates possible non-tomato salmonella sources.
Three weeks after the Food and Drug Administration warned consumers to avoid certain types of tomatoes linked to the salmonella outbreak, people are still falling ill, says Robert Tauxe with the Centers for Disease Control and Prevention. The latest numbers as of Monday afternoon were 851 cases, some of whom fell ill as recently as June 20, says Tauxe, deputy director of the CDC’s division of foodborne diseases.
The CDC launched a new round of interviews over the weekend. “We’re broadening the investigation to be sure it encompasses food items that are commonly consumed with tomatoes,” Tauxe says. If another food is found to be the culprit after tomatoes were recalled nationwide and the produce industry sustained losses of hundreds of millions of dollars, food safety experts say the public’s trust in the government’s ability to track foodborne illnesses will be shattered.
“It’s going to fundamentally rewrite how we do outbreak investigations in this country,” says Michael Osterholm of the Center for Infectious Disease Research and Policy at the University of Minnesota. “We can’t let this investigation, however it might turn out, end with just the answer of ‘What caused it?’ We need to take a very in-depth look at foodborne disease investigation as we do it today.”
I am inclined to believe the FDA is not enough focused on food safety. Perhaps we are not funding it enough, but we sure are spending tons of money on something so I can’t believe more money needs to be spent. Maybe just fewer bills passed (that the politicians don’t even bother to read) with favors to special interests instead of funding to support science and food safety. Or perhaps we are funding enough (though I am skeptical of this contention) and we just are not allowing food safety to get in the way of what special interests want (so we fund plenty for FDA to have managed this much better, to have systems in place that would provide better evidence but they are either prevented from doing so or failed to do so). I am inclined to believe special interests have more sway in agencies like (NASA, EPA, FDA…) than the public good and scientific openness - which is very sad. And, it seems to me, politicians have overwhelmingly chosen not to support more science in places like FDA, CDC, NIH… while increasing federal spending in other areas dramatically.
Related: USDA’s failure to protect the food supply - FDA May Make Decision That Will Speed Antibiotic Drug Resistance - Food safety proposal: throw the bums out - The A to Z Guide to Political Interference in Science
Fermilab was once the premiere particle physics research lab. It is still a very important research lab. But, I have said before, other countries are the ones making the larger efforts lately to invest in science and technology centers of excellence that the US was making in the 1960’s and 1970’s: Economic Strength Through Technology Leadership, Investing in Technology Excellence, etc..
I have also said that the past success of the US has left it in a still very strong position. For example, the anonymous donor that saved Fermilab with a $5 million donation likely benefited from the successful investments in science centers of excellence in the past (few countries - maybe 30, can rely on large donations from wealthy individuals, to sustain centers of excellence and I don’t think any approach what the USA has now - Howard Hughes Medical Institute, Standford, MIT…).
Excellent post on the the saving of Fermilab, To the person who saved Fermilab: Thank You.:
To some, the construction of the Large Hadron Collider at CERN may seem to reduce the importance of Fermilab’s capabilities, but this is not at all the case. Although the LHC may take the title for the overall size and energy levels of a particle accelerator, Fermilab remains a uniquely capable particle physics research institution. Though less powerful, the Tevatron is able to operate for longer periods of time than the LHC and will likely require less downtime for maintenance, allowing for greater access and numerous types of research activities.
Related: CERN Pressure Test Failure - posts on funding science research - Matter to Anti-Matter 3 Trillion Times a Second - Google Investing Huge Sums in Renewable Energy - Gates Foundation and Rotary Pledge $200 Million to Fight Polio - Washington Waste - Washington Paying Out Money it Doesn’t Have - Proposal to Triple NSF GFRP Awards and the Size of the Awards by 33%
Quakes lakes risk ’slurry tsunami’
Related: Quake Lifts Island Ten Feet Out of Ocean - Civil Engineers: USA Infrastructure Needs Improvement - China’s Technology Savvy Leadership - Megaflood Created the English Channel
Google, Chevron Build Mirrors in Desert to Beat Coal With Solar
The 1,000-acre plant uses concentrated sunlight to generate power for as many as 112,500 homes in Southern California. Rising natural gas prices and emissions limits may make solar thermal the fastest-growing energy source in the next decade, say backers including Vinod Khosla, the founder of computer maker Sun Microsystems Inc. Costs for the technology will fall below coal as soon as 2020, the U.S. government estimates.
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“Solar thermal can provide a substantial amount of our power, more than 50 percent,” says Khosla
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Nine solar thermal plants built in the California desert from 1985 to 1991 still operate, with Juno Beach, Florida-based FPL Group Inc. running seven. They have combined capacity of 354 megawatts, enough to power 230,000 Southern California homes. Development slowed when Congress eliminated tax credits for alternative energy in the early 1990s. Laws put in place in 2005 give solar investors a 30 percent tax credit.
Great progress is being made adding wind and solar capacity. And the increasing oil prices are encouraging much faster adoption of these technologies. The promise of widespread adoption is rapidly becoming a reality.
Related: Solar Energy: Economics, Government and Technology - Wind Power Potential to Produce 20% of Electricity Supply by 2030 - Google Investing Huge Sums in Renewable Energy - Solar Tower Power Generation
Germany bans chemicals linked to honeybee devastation
The move follows reports from German beekeepers in the Baden-Württemberg region that two thirds of their bees died earlier this month following the application of a pesticide called clothianidin. “It’s a real bee emergency,” said Manfred Hederer, president of the German Professional Beekeepers’ Association. “50-60% of the bees have died on average and some beekeepers have lost all their hives.” Tests on dead bees showed that 99% of those examined had a build-up of clothianidin.
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The company says an application error by the seed company which failed to use the glue-like substance that sticks the pesticide to the seed, led to the chemical getting into the air.
Related: The Study of Bee Colony Collapses Continues - Bye Bye Bees - Scientists Search for Clues To Bee Mystery
I have written about the continued decline in the relative position of science in the USA compared to the rest of the world: Engineering the Future Economy - Economic Strength Through Technology Leadership - The Best Research Universities - U.S. Slipping on Science - Diplomacy and Science Research - Scientists and Engineers in Congress. The USA continues to act as though the rewards for scientific excellence automatically go to the USA. That isn’t the case and as many other countries make smart investments in scientific centers of excellence the USA chooses to do very little.
Has U.S. Science Lost Its Competitive Edge?
As I have said many times the consequences of failing to take sensible action today will be large. Science and engineering centers of excellence have been a very important factor in the economic success of the USA.
Wind energy has been growing tremendously. In 2000 there were 2,500 megawatts (MW) of installed wind capacity in the United States. By the end of 2007, the U.S. installed capacity exceeded 16,000. A recent Department of Energy report sees the potential to provide up to 20% of our nation’s electrical supply via wind power by 2030.
Related: Global Wind Power Installed Capacity - Electricity Savings - Google Investing Huge Sums in Renewable Energy
I have posted before about the overfishing problems: Fishless Future - SelFISHing - Chinook Salmon Vanish Without a Trace. Here is an emotional article on the problem - How the world’s oceans are running out of fish
Top Science and Math Teachers Receive Presidential Award
Each winner receives a $10,000 award from NSF, as well as a trip for two to Washington, D.C., for a week of celebratory events and professional development activities.
Among the activities during that week are a day with scientists and science educators at NSF; meetings with members of Congress and federal agency leadership; and a reception and dinner at the U.S. Department of State featuring guest speaker Dorothy Metcalf-Lindenburger, a NASA Astronaut-Mission Specialist.
Related: Presidential Award for Excellence in Mathematics and Science Teaching - Einstein Fellowship for Teachers - NSF Graduate Teaching Fellows in K-12 Education - The Importance of Science Education - Education Resources Directory for Science and Engineering
By increasing the production of wheat it is said Norman Borlaug has saved more lives than anyone else who ever lived, for which he was awarded the 1970 Nobel Peace Prize. See his New York Times opinion piece: Stem Rust Never Sleeps
In the last decade, global wheat production has not kept pace with rising population, or the increasing per capita demand for wheat products in newly industrializing countries. At the same time, international support for wheat research has declined significantly. And as a consequence, in 2007-08, world wheat stocks (as a percentage of demand) dropped to their lowest level since 1947-48. And prices have steadily climbed to the highest level in 25 years.
The new strains of stem rust, called Ug99 because they were discovered in Uganda in 1999, are much more dangerous than those that, 50 years ago, destroyed as much as 20 percent of the American wheat crop. Today’s lush, high-yielding wheat fields on vast irrigated tracts are ideal environments for the fungus to multiply, so the potential for crop loss is greater than ever.
If publicly financed international researchers move together aggressively and systematically, high-yielding replacement wheat varieties can be developed and made available to farmers before stem rust disease becomes a global epidemic.
The Bush administration was initially quick to grasp Ug99’s threat to American wheat production. In 2005, Mike Johanns, then secretary of agriculture, instructed the federal agriculture research service to take the lead in developing an international strategy to deal with stem rust. In 2006, the Agency for International Development mobilized emergency financing to help African and Asian countries accelerate needed wheat research.
But more recently, the administration has begun reversing direction. The State Department is recommending ending American support for the international agricultural research centers that helped start the Green Revolution, including all money for wheat research. And significant financial cuts have been proposed for important research centers, including the Department of Agriculture’s essential rust research laboratory in St. Paul.
This shocking short-sightedness goes against the interests not only of American wheat farmers and consumers but of all humanity. It is tantamount to the United States abandoning its pledge to help halve world hunger by 2015.
Related: Diplomacy and Science Research - Five Scientists Who Made the Modern World - 2004 Medal of Science Winners - U.S. Slipping on Science
Science Studio offers podcasts by the Arizona State University School of Life Sciences with professors discussing science; it is another excellent source of science podcasts. Podcasts include:
These podcasts are great way to use the internet to serve the mission of universities: to educate. And a great way to promote science.
Related: Lectures from the Stanford Linear Accelerator Center - UC-Berkeley Course Videos - Science Podcast Libraries - Communicating Science to the Public
The NASA Science Mission Directorate sponsors scientific research, and develops and deploys satellites and probes in collaboration with NASA’s partners around the world to answer fundamental questions requiring the view from and into space. SMD seeks to understand the origins, evolution, and destiny of the universe and to understand the nature of the phenomena that shape it. SMD also seeks to understand:
* the nature of life in the universe and what kinds of life may exist beyond Earth;
* the solar system, both scientifically and in preparation for human exploration; and
* the Sun and Earth, changes in the Earth-Sun system, and the consequences of the Earth-Sun relationship for life on Earth.
Maybe, for this site NASA actually listened to the engineers: as this site works rather than making false claims about the visitor’s browser. The site includes content specifically targeted at teachers, students, researchers and the general public.
Related: Great Self Portrait - Boiling Water in Space - Mars Rovers Getting Ready for Another Adventure
An American Solar Opportunity Gets Shipped Abroad
They’ll be installed in Europe. In Asia. And maybe even in America too, one day. Why not now? Because AES wants to sow its solar seeds in only those countries that offer the most “attractive tariffs.” That eliminates the US from the list of potentials, immediately. And it gives countries like Germany, Spain, Italy and South Korea the clear advantage. They all have can’t-beat national incentives for solar developers.
It’s one of the sad facts of Washington’s incoherent clean energy policy these days. How can a country lure in clean energy projects when there are far more appealing offers elsewhere?
Government actions impact economic decisions. It will likely take more than 10 years to have good data on what government investments pay off in the energy sector. But I would say it is a pretty good bet to invest in technology such as: solar, geothermal, wind… Countries that create global centers of excellence in these areas are likely to benefit greatly. The only question I think is that many countries are smart enough to see the benefits and so likely many countries will try.
Any time many actors pursue the same economic strategy there is the risk that the payoff is diluted with so many others having done the same thing. Still the reason so many countries have adopted the strategy of developing centers of excellence in science, engineering and technology is that it is such a good idea. The USA has a problem in that we are spending more than we produce on luxuries today so there is much less available to invest compared to other countries (and compared to 40 years ago).
Related: Global Installed Capacity of Wind Power - Invest in Science for a Strong Economy - Science, Engineering and the Future of the American Economy - China challenges scientific research dominance of USA, Europe and Japan - Green Energy in Canada
Kim Carr, Minister for Innovation, Australia, speech to the National Press Club of Australia: Science meets Parliament
When societies invest in science, they are investing in their own future. They are entitled to expect a fair return on that investment.
They’re entitled to know we are using the country’s intellectual and technical capacity to deliver outcomes that matter to them – stronger communities, more good jobs, a cleaner environment, better public services, a richer culture, greater security for themselves and their children. Everybody here knows the rules of professional scientific conduct – think independently, put emotion aside, reject received authority, be faithful to the evidence, communicate openly.
These are good rules – rules I wholeheartedly endorse – but there’s one more I’d like to add – remember your humanity. Remember you’re part of a wider society – one that you have a special ability and therefore a special duty to serve. This doesn’t just apply in the physical sciences, but in the humanities and social sciences as well. When I say science I mean knowledge in all its forms.
Related: Engineering Economic Benefits - Authors of Scientific Articles by Country - Economic Strength Through Technology Leadership - Science and Engineering in Global Economics - Aussies Look to Finnish Innovation Model - Invest in Science for a Strong Economy
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Go to NASA’s web site. Use the security settings that are most intelligent to use, the NoScript plugin for Firefox, and NASA makes this bold pointy haired boss statement at the top of every page:
“There’s a problem with your browser or settings.
Your browser or your browser’s settings are not supported. To get the best experience possible, please download a compatible browser. If you know your browser is up to date, you should check to ensure that javascript is enabled.”
Well no, there is no problem with my browser settings. And I am using the latest version of the most popular browser. 0 for 2 phb. What you mean to say is: I am so lame I hired someone who designed our web site so it fails to work properly without javascript enabled.
Jeez, get someone who know how to program a web site that just works. Any marginally competent individual can have your site work for any modern browser and then add in extra features people can take advantage using javascript, or flash or whatever extra things you want. It is amazing that an agency that is suppose to know about technology can do such a lame job of producing a web site. They do manage to provide good content for their web site (probably the content is provided by engineers while some phb decides they know what is best for the web site code).
Related: Astronaut and Earth - Usability Failures at the Royal Society Web Site - NSF Usability Failure - Webcasts by Chemistry and Physics Nobel Laureates
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