Science and Engineering: Innovation, Research, Education and Economics
Research Category
Posts about scientific research and development as well as science and engineering breakthroughs.
Recommended posts: R&D Spending in USA Universities - Diplomacy and Science Research - Research Career in Industry or Academia - New Understanding of Human DNA - Basic Science Research Funding - The World’s Best Research Universities - Mystery of High-Temperature Superconductivity - Why Most Published Research Findings Are False
May 7, 2008

Elephants Classify Human Ethnic Groups that Hunt Them by Odor

Wash Your Clothes: Elephants Can Smell You a Mile Away

…in Amboseli National Park in Kenya. Elephants in the region encounter different ethnic groups, including the Maasai, whose young men spear elephants, and the Kamba, agricultural villagers who pose no threat at all.

The researchers observed elephants exposed to the scent from identical cloth garments, some worn by Maasai men, others by Kamba men and some that were unworn. The Maasai scent produced the strongest reactions, with elephants moving farther and faster to distance themselves from the odor source, often not stopping until reaching tall grass. The elephants also took far longer to calm down than those exposed to scents from the Kamba and unworn cloths.

Related: Fighting Elephant Poaching With Science - Effect of People on Other Species - Water Buffaloes, Lions and Crocodiles Oh My - Curious Cat Travel Photos: Kenya

May 5, 2008

Molecular Action May Help Keep Birds on Course

Molecular Action May Help Keep Birds on Course

Four decades after scientists showed that migratory birds use Earth’s magnetic field to orient themselves during their seasonal journeys, researchers have at last found a molecular mechanism that may explain how they do it.

If the hypothesis is true, the planet’s magnetic field lines — which arch around Earth from north to south — may be plainly visible to birds, like the dashed line in the middle of a road.

The work, described online yesterday in the journal Nature, was conducted in a test tube and does not prove that birds actually use the mechanism. And researchers aligned with a competing model say they are not convinced.

But by identifying for the first time a molecule that reacts to very weak magnetic fields, the experiments prove the plausibility of a long-hypothesized method of avian navigation that has had a credibility problem because no one had ever found a molecule with the required sensitivity.

Related: Monarch Butterfly Migration - Mini Helicopter Masters Insect Navigation Trick - Other bird tagged posts

Fat Cell Count Set in Childhood

Fat cell number is set in childhood and stays constant in adulthood

As fat people have an abundance of fat tissue, the natural assumption is that fat people have more fat cells, or ‘adipocytes’. That’s only part of the story - it turns out that overweight and obese people not only have a surplus of fat cells, they have larger ones too.

During adulthood, about 8% of fat cells die every year only to be replaced by new ones. As a result, adults have a constant number of fat cells, even those who lose masses of weight. Instead, it’s changes in the volume of fat cells that causes body weight to rise and fall.

we couldn’t have a clearer indication of the importance of childhood as a window for preventing obesity and the chronic diseases affected by it - cancer, heart disease, diabetes and more.

The message is especially stark following the recent Foresight report, which estimated that if current trends are left unchecked, by 2050 a quarter of all UK children under the age of 16 will be obese. The knowledge that their fat cell count will then be set for life makes the cost of inaction even higher. Fortunately, it seems that the UK Government is taking appropriate steps and recently pledged over a third of a billion pounds on a concerted strategy to tackle childhood obesity.

Related: $500 Million to Reduce Childhood Obesity in USA - Obesity Epidemic Explained - Kind Of - Drinking Soda and Obesity

May 3, 2008

Colony Collapse Disorder Continues

1.1 Million Bee Colonies Dead This Year

The information provided here was generated by a survey conducted by the Apiary Inspectors of America. They took the survey in January and February this year, and in the process, gathered information from 18% of the colonies in the U.S.

The survey found that about 35% of all the colonies in the U.S. died last winter. Of those that died, 71% died of natural causes, 29% from symptoms that are suspect colony collapse disorder. Doing the math that comes to at least 10% of all the bees in the U.S. last year died of Colony Collapse Disorder.

Considering all these factors, undue concern over IAPV detection is not warranted. While IAPV’s role in colony losses remains a priority in ongoing research, we do know that high levels of other common bee viruses, such as KBV, DWV, and ABPV, have also been linked with certain incidences of high colony mortality or decline in worker numbers. We also know that nearly all bee colonies are infected with at least one type of virus and that all these viruses are potentially pathogenic.

The research continues. As I have said before this is a great example of scientists in action trying to figure out what is happening.

Related: The Study of Bee Colony Collapses Continues - Bye Bye Bees - Scientists Search for Clues To Bee Mystery

April 29, 2008

Engineering Sports at MIT

Making sports an exact science by Shira Springer

“It’s all about finding your passion,” said Vasquez, the group leader and a Material Science and Engineering major. “All the guys on the [project] team love sports. It’s more fun than what you typically think of with an MIT research project.

“There are very few sports companies that put value in good engineering, in terms of projects that make engineering sense rather than just marketing sense. When you get to see how your research can actually be used, it’s pretty cool.”

The MIT Sports Innovation program, though, was designed to give undergraduates hands-on research experience away from textbooks and classrooms. Working in a Building 17 laboratory cluttered with experiments, where the hum of the wind tunnel can make conversation difficult, the undergraduates brainstorm and build different components of the test setup.

Inside the laboratory and Aero/Astro hangar, the MIT baseball research project looks like a combination of shop class and horror flick: Power tools, quick-drying cement, PVC pipe, handsaws, and mannequin parts are scattered around.

Related: Baseball Pitch Designed in the Lab - Randomization in Sports - The Science of the Football Swerve - Sports Engineering at MIT (2006)

April 27, 2008

Wheat Rust Research

By increasing the production of wheat it is said Norman Borlaug has saved more lives than anyone else who ever lived, for which he was awarded the 1970 Nobel Peace Prize. See his New York Times opinion piece: Stem Rust Never Sleeps

Today, wheat provides about 20 percent of the food calories for the world’s people. The world wheat harvest now stands at about 600 million metric tons.

In the last decade, global wheat production has not kept pace with rising population, or the increasing per capita demand for wheat products in newly industrializing countries. At the same time, international support for wheat research has declined significantly. And as a consequence, in 2007-08, world wheat stocks (as a percentage of demand) dropped to their lowest level since 1947-48. And prices have steadily climbed to the highest level in 25 years.

The new strains of stem rust, called Ug99 because they were discovered in Uganda in 1999, are much more dangerous than those that, 50 years ago, destroyed as much as 20 percent of the American wheat crop. Today’s lush, high-yielding wheat fields on vast irrigated tracts are ideal environments for the fungus to multiply, so the potential for crop loss is greater than ever.

If publicly financed international researchers move together aggressively and systematically, high-yielding replacement wheat varieties can be developed and made available to farmers before stem rust disease becomes a global epidemic.

The Bush administration was initially quick to grasp Ug99’s threat to American wheat production. In 2005, Mike Johanns, then secretary of agriculture, instructed the federal agriculture research service to take the lead in developing an international strategy to deal with stem rust. In 2006, the Agency for International Development mobilized emergency financing to help African and Asian countries accelerate needed wheat research.

But more recently, the administration has begun reversing direction. The State Department is recommending ending American support for the international agricultural research centers that helped start the Green Revolution, including all money for wheat research. And significant financial cuts have been proposed for important research centers, including the Department of Agriculture’s essential rust research laboratory in St. Paul.

This shocking short-sightedness goes against the interests not only of American wheat farmers and consumers but of all humanity. It is tantamount to the United States abandoning its pledge to help halve world hunger by 2015.

Related: Diplomacy and Science Research - Five Scientists Who Made the Modern World - 2004 Medal of Science Winners - U.S. Slipping on Science

April 25, 2008

Gecko-inspired Bandage

MIT creates gecko-inspired bandage

Drawing on some of the principles that make gecko feet unique, the surface of the bandage has the same kind of nanoscale hills and valleys that allow the lizards to cling to walls and ceilings. Layered over this landscape is a thin coating of glue that helps the bandage stick in wet environments, such as to heart, bladder or lung tissue. And because the bandage is biodegradable, it dissolves over time and does not have to be removed.

Gecko-like dry adhesives have been around since about 2001 but there have been significant challenges to adapt this technology for medical applications given the strict design criteria required. For use in the body, they must be adapted to stick in a wet environment and be constructed from materials customized for medical applications. Such materials must be biocompatible, meaning they do not cause inflammation; biodegradable, meaning they dissolve over time without producing toxins; and elastic, so that they can conform to and stretch with the body’s tissues.

When tested against the intestinal tissue samples from pigs, the nanopatterned adhesive bonds were twice as strong as unpatterned adhesives. In tests of the new adhesive in living rats, the glue-coated nanopatterned adhesive showed over a 100 percent increase in adhesive strength compared to the same material without the glue. Moreover, the rats showed only a mild inflammatory response to the adhesive, a minor reaction that does not need to be overcome for clinical use.

Among other advantages, the adhesive could be infused with drugs designed to release as the biorubber degrades. Further, the elasticity and degradation rate of the biorubber are tunable, as is the pillared landscape. This means that the new adhesives can be customized to have the right elasticity, resilience and grip for different medical applications.

Related: Gecko Tape - Gel Stops Bleeding in Seconds

April 18, 2008

Biodegradable Plastic Bags and Bottles

researchers look to make environmentally friendly plastics

Every year, more than 30 billion water bottles are added to America’s landfills, creating a mountainous environmental problem. But if research at Missouri University of Science and Technology is successful, the plastic bottles of the future could literally disappear within four months of being discarded.

The Missouri S&T research team is constructing new breeds of biodegradable and bioavailable plastics in an effort to reduce the tons of plastic waste that ends up in the nation’s landfills each year. Bioavailable plastics contain substances that can be absorbed by living systems during their normal physiological functions.

By combining and modifying a variety of bio-based, oil-based and natural polymers, the team seeks to create optimal blends that can be used to make agricultural films, bottles, biomedical and drug delivery devices, and more.

As polylactic acid degrades, the material reacts with water to decompose into small molecules, which are then mineralized into water and carbon dioxide.

“In general, the main end products of polymer degradation are water and carbon dioxide,” Shahlari explains. “Polylatic acid has the potential of replacing the regular water bottles, and we anticipate that our research could be incorporated into that field too.

It sure seems like they are saying these would really biodegrade. Plastic bags can photodegrade where they break down into small bits of plastic that might be hard to see but are still toxic that can be eaten by animals, and us. As one would figure - that is not a good thing. The ocean garbage floats are not huge amounts of plastic bags and bottles but instead huge amounts of small and tiny plastic particles. I know using corn based bags has been looked at previously and used.

Related: New Plastic Bags Biodegrade in Four Months - Manufacturers Push Biodegradable Plastic Bags (NPR podcast) - Crisis at Sea

April 14, 2008

Bikini Atoll 50 Years Later

Nuked coral reef bounces back

Three islands of Bikini Atoll were vapourised by the Bravo hydrogen bomb in 1954, which shook islands 200 kilometres away. Instead of finding a bare underwater moonscape, ecologists who have dived it have given the 2-kilometre-wide crater a clean bill of health.

“It was fascinating – I’ve never seen corals growing like trees outside of the Marshall Islands,” says Zoe Richards of the ARC Centre of Excellence for Coral Reef Studies in Australia. Richards and colleagues report a thriving ecosystem of 183 species of coral, some of which were 8 metres high. They estimate that the diversity of species represents about 65% of what was present before the atomic tests. The ecologists think the nearby Rongelap Atoll is seeding the Bikini Atoll, and the lack of human disturbance is helping its recovery.

“When I put the Geiger counter near a coconut, which accumulates radioactive material from the soil, it went berserk,” says Beger.

Related: Quake Lifts Island Ten Feet Out of Ocean - Bacterium Living with High Level Radiation - Artic Seed Vault

April 10, 2008

Self-assembling Nanofibers Heal Spinal Cords in Mice

Self-assembling Nanofibers Heal Spinal Cords by Prachi Patel-Predd

An engineered material that can be injected into damaged spinal cords could help prevent scars and encourage damaged nerve fibers to grow. The liquid material, developed by Northwestern University materials science professor Samuel Stupp, contains molecules that self-assemble into nanofibers, which act as a scaffold on which nerve fibers grow.

Stupp and his colleagues described in a recent paper in the Journal of Neuroscience that treatment with the material restores function to the hind legs of paralyzed mice.

The new work is the first test for the material to heal spinal cord injuries in animals. And Kessler says that it worked better than the researchers expected. The researchers stimulated a spinal cord injury in mice and injected the material 24 hours later. They found that the material reduced the size of scars and stimulated the growth of the nerve fibers through the scars. It promoted the growth of both types of nerve fibers that make up the spinal cord: motor fibers that carry signals from the brain to the limbs, and sensory fibers that carry sense signals to the brain. What is more, the material encouraged the nerve stem cells to mature into cells that create myelin–an insulating layer around nerve fibers that helps them to conduct signals more effectively.

Related: Using Bacteria to Carry Nanoparticles Into Cells - Micro-robots to ’swim’ Through Veins - Nanowired at Berkeley

April 8, 2008

Clay Versus MRSA Superbug

“Healing clays” hold promise in fight against MRSA superbug infections and disease

Scientists from Arizona State University report that minerals from clay promise could provide inexpensive, highly-effective antimicrobials to fight methicillin-resistant Staphylococcus aureus (MRSA) infections that are moving out of health care settings and into the community.

Unlike conventional antibiotics routinely administered by injection or pills, the so-called “healing clays” could be applied as rub-on creams or ointments to keep MRSA infections from spreading

In their latest study, funded by the National Institutes of Health, Williams, Haydel and their colleagues collected more than 20 different clay samples from around the world to investigate their antibacterial activities… The researchers identified at least two clays from the United States that kill or significantly reduce the growth of these bacteria

Also listen to a podcast with the researchers, Lynda Williams and Shelly Haydel, that provides much more detail. The Science Studio podcasts from Arizona State University provides great science podcasts.

Related: Soil Could Shed Light on Antibiotic Resistance - Entirely New Antibiotic Developed - Science Webcast Directory - NSF Awards $50 Million for Collaborative Plant Biology Project (University of Arizona)

April 5, 2008

Scientists Witness the Birth of a Brain Cell

The Birth of a Brain Cell: Scientists Witness Neurogenesis

For the first time, researchers have developed a way to view stem cells in the brains of living animals, including humans—a finding that allows scientists to follow the process neurogenesis (the birth of neurons). The discovery comes just months after scientists confirmed that such cells are generated in adult as well as developing brains.

The key ingredient in this process is a substance unique to immature cells that is neither found in mature neurons nor in glia, the brain’s nonneuronal support cells. Maletic-Savatic and her colleagues collected samples of each of the three cell types from rat brains (stem cells from embryonic animals, the others from adults) and cultured the varieties separately in the lab. They were able to determine the chemical makeup of each variety - and isolate the compound unique to stem cells - with nuclear magnetic resonance (NMR) spectroscopy. (NMR helps to determine a molecule’s structure by measuring the magnetic properties of its subatomic particles.) Although the NMR could identify the biomarker, but not its makeup, Maletic-Savatic speculates it is a blend of fatty acids in a lipid (fat) or lipid protein.

Related: Feed your Newborn Neurons - Brain Development - New Neurons in Old Brains - No Sleep, No New Brain Cells

March 28, 2008

Squid Materials Engineering

Scientists find that squid beak is both hard and soft

The sharp beak of the Humboldt squid is one of the hardest and stiffest organic materials known. Engineers, biologists, and marine scientists at the University of California, Santa Barbara, have joined forces to discover how the soft, gelatinous squid can operate its knife-like beak without tearing itself to pieces.

The key to the squid beak lies in the gradations of stiffness. The tip is extremely stiff, yet the base is 100 times more compliant, allowing it to blend with surrounding tissue. However, this only works when the base of the beak is wet. After it dries out, the base becomes similarly stiff as the already desiccated beak tip.

“You can imagine the problems you’d encounter if you attached a knife blade to a block of Jell-o and tried to use that blade for cutting. The blade would cut through the Jell-o at least as much as the targeted object. In the case of the squid beak, nature takes care of the problem by changing the beak composition progressively, rather than abruptly, so that its tip can pierce prey without harming the squid in the process. It’s a truly fascinating design!”

“If we could reproduce the property gradients that we find in squid beak, it would open new possibilities for joining materials,” explained Zok. “For example, if you graded an adhesive to make its properties match one material on one side and the other material on the other side, you could potentially form a much more robust bond,” he said. “This could really revolutionize the way engineers think about attaching materials together.”

Related: Deep-Sea Giant Squid - Self Healing Plastic - Sea Slug Photo Gallery

March 23, 2008

6 Inch Bat Plane

image of bat plane

A six-inch robotic spy plane modeled after a bat would gather data from sights, sounds and smells in urban combat zones and transmit information back to a soldier in real time.

That’s the Army’s concept, and it has awarded the University of Michigan College of Engineering a five-year, $10-million grant to help make it happen. The grant establishes the U-M Center for Objective Microelectronics and Biomimetic Advanced Technology, called COM-BAT for short. The grant includes an option to renew for an additional five years and $12.5 million.

U-M researchers will focus on the microelectronics. They will develop sensors, communication tools and batteries for this micro-aerial vehicle that’s been dubbed “the bat.” Engineers envision tiny cameras for stereo vision, an array of mini microphones that could home in on sounds from different directions, and small detectors for nuclear radiation and poisonous gases.

Low-power miniaturized radar and a very sensitive navigation system would help the bat find its way at night. Energy scavenging from solar, wind, vibration and other sources would recharge the bat’s lithium battery. The aircraft would use radio to send signals back to troops.

“These are all concepts, and many of them are the next generation of devices we have already developed. We’re trying to push the edge of our technologies to achieve functionality that was not possible before,” said Kamal Sarabandi, the COM-BAT director and a professor in the U-M Department of Electrical Engineering and Computer Science.

COM-BAT also involves the University of California at Berkeley and the University of New Mexico. It is one of four centers the Army launched as a collaborative effort among industry, academia and the Army Research Laboratory to work toward this vision of a small, robotic aircraft that could sense and communicate. Each of the four centers is charged with developing a different subsystem of the bat, a self-directed sensor inspired by the real thing.
(more…)

March 19, 2008

Explaining the Missing Antimatter

Flipping particle could explain missing antimatter

It is one the biggest mysteries in physics - where did all the antimatter go? Now a team of physicists claims to have found the first ever hint of an answer in experimental data. The findings could signal a major crack in the standard model, the theoretical edifice that describes nature’s fundamental particles and forces.

In its early days, the cosmos was a cauldron of radiation and equal amounts of matter and antimatter. As it cooled, all the antimatter annihilated in collisions with matter - but for some reason the proportions ended up lopsided, leaving some of the matter intact.

Physicists think the explanation for this lies with the weak nuclear force, which differs from the other fundamental forces in that it does not act equally on matter and antimatter. This asymmetry, called CP violation, could have allowed the matter to survive to form the elements, stars and galaxies we see today.

“It is tantalisingly interesting at the moment,” says Val Gibson, an expert on B meson physics at the University of Cambridge. “If it is true, it is earth-shattering.” Jacobo Konigsberg, who leads the CDF collaboration, says that Tevatron researchers are “cautiously excited” about the analysis. He points out that more data needs to be analysed to rule out a statistical fluke, which has happened several times before in particle physics.

Related: First Evidence of New Physics in b <--> s Transitions (research paper) - posts tagged physics - Matter to Anti-Matter 3 Trillion Times a Second - Quantum Mechanics Made Relatively Simple Podcasts

March 17, 2008

Drug Price Crisis

I don’t think the suggestion below really solves the drug price crisis. But I do think it is an example of an educational and research institution actually proposing sensible role for themselves. As I have said too many universities now act like they are for-profit drug or research companies: Funding Medical Research. For some background on drug prices read my post on the Curious Cat Management blog from 2005.

Solving the drug price crisis

The mounting U.S. drug price crisis can be contained and eventually reversed by separating drug discovery from drug marketing and by establishing a non-profit company to oversee funding for new medicines, according to two MIT experts on the pharmaceutical industry.

Following the utility model, Finkelstein and Temin propose establishing an independent, public, non-profit Drug Development Corporation (DDC), which would act as an intermediary between the two new industry segments — just as the electric grid acts as an intermediary between energy generators and distributors.

The DDC also would serve as a mechanism for prioritizing drugs for development, noted Finkelstein. “It is a two-level program in which scientists and other experts would recommend to decision-makers which kinds of drugs to fund the most. This would insulate development decisions from the political winds,” he said.

Book - Reasonable Rx: Solving the Drug Price Crisis by Stan Finkelstein and Peter Temin

Related: Lifestyle Drugs and Risk - From Ghost Writing to Ghost Management in Medical Journals - USA Spent $2.1 Trillion on Health Care in 2006 - Measuring the Health of Nations - Economic Strength Through Technology Leadership - USA Paying More for Health Care

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