Virus Engineered To Kill Deadly Brain Tumors

Posted on February 24, 2008  Comments (1)

Yale Lab Engineers Virus That Can Kill Deadly Brain Tumors

A laboratory-engineered virus that can find its way through the vascular system and kill deadly brain tumors has been developed by Yale School of Medicine researchers, it was reported this week in the Journal of Neuroscience.

Each year 200,000 people in the United States are diagnosed with a brain tumor, and metastatic tumors and glioblastomas make up a large part of these tumors. There currently is no cure for these types of tumors, and they generally result in death within months.

“Three days after inoculation, the tumors were completely or almost completely infected with the virus and the tumor cells were dying or dead,” van den Pol said. “We were able to target different types of cancer cells. Within the same time frame, normal mouse brain cells or normal human brain cells transplanted into mice were spared. This underlines the virus’ potential therapeutic value against multiple types of brain cancers.”

Pretty cool. Too bad these press releases never quite live up to the initial promise. Still this one is very cool, if it can succeed in helping even a small percentage of people it will be a great breakthrough. It is also just cool – using a virus to kill tumors – how cool is that?

Related: What are viruses?Using Bacteria to Carry Nanoparticles Into CellsCancer Cure, Not so FastCancer cell ‘executioner’ foundCancer Deaths not a Declining TrendUsing Viruses to Construct Electrodes and More

One Response to “Virus Engineered To Kill Deadly Brain Tumors”

  1. Curious Cat Science and Engineering Blog » Potential Viral Therapy for Difficult Cancers
    April 23rd, 2008 @ 9:05 am

    “Combining a herpes virus genetically altered to express a drug-enhancing enzyme with a chemotherapy drug effectively and safely reduced the size of highly malignant human sarcoma grafted into mice…”

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