Tool use is rare in wild animals, but of widespread interest because of its relationship to animal cognition, social learning and culture. Despite such attention, quantifying the costs and benefits of tool use has been difficult, largely because if tool use occurs, all population members typically exhibit the behavior. In Shark Bay, Australia, only a subset of the bottlenose dolphin population uses marine sponges as tools, providing an opportunity to assess both proximate and ultimate costs and benefits and document patterns of transmission.

We compared sponge-carrying (sponger) females to non-sponge-carrying (non-sponger) females and show that spongers were more solitary, spent more time in deep water channel habitats, dived for longer durations, and devoted more time to foraging than non-spongers; and, even with these potential proximate costs, calving success of sponger females was not significantly different from non-spongers. We also show a clear female-bias in the ontogeny of sponging. With a solitary lifestyle, specialization, and high foraging demands, spongers used tools more than any non-human animal. We suggest that the ecological, social, and developmental mechanisms involved likely (1) help explain the high intrapopulation variation in female behaviour, (2) indicate tradeoffs (e.g., time allocation) between ecological and social factors and, (3) constrain the spread of this innovation to primarily vertical transmission.

Adrian Thompson, who works at the university’s Centre for Computational Neuroscience and Robotics, came up with the idea of self-designing circuits while thinking about building neural network chips. A graduate in microelectronics, he joined the centre four years ago to pursue a PhD in neural networks and robotics.
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To get the experiment started, he created an initial population of 50 random circuit designs coded as binary strings. The genetic algorithm, running on a standard PC, downloaded each design to the Field Programmable Gate Arrays (FPGA) and tested it with the two tones generated by the PC’s sound card. At first there was almost no evidence of any ability to discriminate between the two tones, so the genetic algorithm simply selected circuits which did not appear to behave entirely randomly. The fittest circuit in the first generation was one that output a steady five-volt signal no matter which tone it heard.

By generation 220 there was some sign of improvement. The fittest circuit could produce an output that mimicked the input - wave forms that corresponded to the 1KHz or 10KHz tones - but not a steady zero or five-volt output.

By generation 650, some evolved circuits gave a steady output to one tone but not the other. It took almost another 1,000 generations to find circuits that could give approximately the right output and another 1,000 to get accurate results. However, there were still some glitches in the results and it took until generation 4,100 for these to disappear. The genetic algorithm was allowed to run for a further 1,000 generations but there were no further changes.

Mission operation is never interrupted. The repair circuitry is sufficiently small that a pair could mutually repair each other. A minimal evolutionary algorithm is used during permanent fault self-repair. Reliability analysis of the studied case shows the system has a 0.99 probability of surviving 17 times the mean time to local permanent fault arrival. Such a system would be 0.99 probable to survive 100 years with one fault every 6 years.

Humans have an innate defence system against deadly bacteria. However, how the step from gene to anti-bacterial effect occurs in the body is not yet known. To date, B. Pseudomallei, a bacterium suitable for bioweapons, had managed to elude medics. It can remain hidden in the human body for many years without being detected by the immune system. The bacteria can suddenly become activated and spread throughout the body, resulting in the patient dying from blood poisoning. AMC physician Joost Wiersinga and the Laboratory for Experimental Internal Medicine discovered which gene-protein combination renders the lethal bacteria B. pseudomallei harmless.

Wiersinga focussed on the so-called Toll-like receptors. These are the proteins that initiate the fight against pathogens. There are currently ten known Toll-like receptors which are located on the outside of immune cells, our body’s defence system. The toll-like receptors jointly function as a 10-figure alarm code. Upon coming into contact with the immune cell each bacterium enters its own Toll code. For known pathogens this sets off an alarm in the immune system and the defence mechanism is activated. Yet B. pseudomallei fools the system by entering the code of a harmless bacterium. As a result the body’s defence system remains on standby.

Yet some people are resistant: they become infected but not ill. Wiersinga found a genetic cause for this resistance. He discovered which toll receptor can fend off B. pseudomallei. He did this by rearing mice DNA in which the gene for Toll2 production was switched on and off. ‘The group where the gene for Toll2 was switched off, survived the bacterial infection’, says Wiersinga. ‘The other receptor that we investigated, Toll4, had no effect - even though for the past ten years medics had regarded this as the most important receptor.’ The ultimate aim of this study is to develop a vaccine.

It also makes perfect sense that our bodies evolved to store energy for worse times (and some of us have bodies better at doing that). Now we are in a new environment where (at least for many people alive today) finding enough calories is not going to be a problem so it would be nice if we could tell our bodies to get less efficient at storing fat

They developed a mathematical model that attributed patterns of speciation to the way that closely related species divide up their environment. According to this model, when there are few relatives around to compete for resources, such as when an environment is first colonized, species differentiate rapidly.
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This model is robust: even when the authors assumed that their phylogenetic tree contains only 25 percent of all Dendroica species, they found that their γ test was still valid, indicating that this genus experienced an explosive bout of adaptive radiation before settling down to a “more normal” rate of speciation.

This mathematical model provides an incisive tool to gain a clearer understanding of the pattern and rate of speciation for groups of closely related species, even in the absence of a fossil record, simply by analyzing their DNA.

The team designed and engineered a metamaterial that uses tiny geometric surface features to successfully capture the electric and magnetic properties of a microwave to the point of total absorption.

“Three things can happen to light when it hits a material,” says Boston College Physicist Willie J. Padilla. “It can be reflected, as in a mirror. It can be transmitted, as with window glass. Or it can be absorbed and turned into heat. This metamaterial has been engineered to ensure that all light is neither reflected nor transmitted, but is turned completely into heat and absorbed. It shows we can design a metamaterial so that at a specific frequency it can absorb all of the photons that fall onto its surface.”
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The metamaterial is the first to demonstrate perfect absorption and unlike conventional absorbers it is constructed solely out of metallic elements, giving the material greater flexibility for applications related to the collection and detection of light, such as imaging, says Padilla, an assistant professor of physics.

Vocal learning is a critical behavioral substrate for spoken human language. It is a rare trait found in three distantly related groups of birds-songbirds, hummingbirds, and parrots. These avian groups have remarkably similar systems of cerebral vocal nuclei for the control of learned vocalizations that are not found in their more closely related vocal non-learning relatives. These findings led to the hypothesis that brain pathways for vocal learning in different groups evolved independently from a common ancestor but under pre-existing constraints. Here, we suggest one constraint, a pre-existing system for movement control.

Using behavioral molecular mapping, we discovered that in songbirds, parrots, and hummingbirds, all cerebral vocal learning nuclei are adjacent to discrete brain areas active during limb and body movements. Similar to the relationships between vocal nuclei activation and singing, activation in the adjacent areas correlated with the amount of movement performed and was independent of auditory and visual input.
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Based upon these findings, we propose a motor theory for the origin of vocal learning, this being that the brain areas specialized for vocal learning in vocal learners evolved as a specialization of a pre-existing motor pathway that controls movement.

Einstein’s general theory of relativity swept Newton away by showing that gravity operates by distorting space itself.

Even Einstein, however, may not have got it right. Modern instruments have shown a departure from his predictions, too. In 1990 mission controllers at the Jet Propulsion Laboratory (JPL) in Pasadena, California, which operates America’s unmanned interplanetary space probes, noticed something odd happen to a Jupiter-bound craft, called Galileo. As it was flung around the Earth in what is known as a slingshot manoeuvre (designed to speed it on its way to the outer solar system), Galileo picked up more velocity than expected. Not much. Four millimetres a second, to be precise. But well within the range that can reliably be detected.
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Altogether, John Anderson and his colleagues analysed six slingshots involving five different spacecraft. Their paper on the matter is about to be published in Physical Review Letters. Crucially for the idea that there really is a systematic flaw in the laws of physics as they are understood today, their data can be described by a simple formula. It is therefore possible to predict what should happen on future occasions.

That is what Dr Anderson and his team have now done. They have worked out the exact amount of extra speed that should be observed when they analyse the data from a slingshot last November, which involved a craft called Rosetta. If their prediction is correct, it will confirm that the phenomenon is real and that their formula is capturing its essence. Although the cause would remain unknown, a likely explanation is that something in the laws of gravity needs radical revision.

This is the first time fish have been seen actively becoming torpid—a state similar to hibernation in land animals—as part of an annual cycle. “A lot of freshwater fish go [unexpectedly] dormant in winter because a drop in temperature lowers their metabolism,” said study co-author Hamish Campbell, a zoologist at the University of Queensland, Australia.

“By contrast, these Antarctic fish actively reduce their ‘cost of living,’” he said… “The fish became 20 times less active in winter compared to summer,”… About every week or so the cod wake up and swim around for a few hours, the team observed. “This is quite similar to ‘denning’ in bears, where the hibernation isn’t so deep and the animals can be disturbed, then spend some time awake before going back to bed,” Fraser said.

In fact the new study added nothing (and it was ridiculously badly reported): we already knew that antidepressants perform only marginally better than placebo, and the National Institute for Health and Clinical Excellence (Nice) guidelines has actively advised against using them in milder depression since 2004. But the more interesting questions are around placebo.
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Another study from 2002 looked at 75 trials of antidepressants over the past 20 years, but looked only at the response in the placebo arms of the trials, and found that the response to placebo has increased significantly in recent years (as has the response to medication): perhaps our expectations of those drugs have increased, or perhaps, conversely to our earlier example, the trial designs have become systematically more flattering. I’m giving you tenuous data, on an interesting area, because I know you’re adult enough to cope with ambiguity.

Long-lasting, insecticide-treated mosquito nets should be distributed free, rapidly and widely in malaria-endemic areas, World Health Organization officials said here Thursday, setting new guidelines for fighting the mosquito-borne disease around the globe.
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The WHO announcement was paired with what Kochi called “impressive” findings by Kenyan health authorities that widespread, free distribution of mosquito nets can effectively save children’s lives.

After several years of using a combination of free distribution and sales, the Kenyan government last year conducted a massive, almost military-style campaign to distribute without charge 3.4 million insecticide-treated mosquito nets over three days in 46 malaria-endemic districts across the country.

Among a monitored group of 3,500 children in four of those districts, the number sleeping under the nets increased nearly tenfold from 2004 to 2006, WHO said, citing Kenyan government figures. The result was 44 percent fewer deaths than among children not sleeping under nets. Insecticide-treated mosquito nets kill mosquitoes on contact. If enough nets are distributed and used, they can have a kind of collective impact of eradicating mosquitoes in a given area.

Over the last few years we have noticed worrisome trends in CS education. The following represents a summary of those trends:
1. Mathematics requirements in CS programs are shrinking.
2. The development of programming skills in several languages is giving way to cookbook approaches using large libraries and special-purpose packages.
3. The resulting set of skills is insufficient for today’s software industry (in particular for safety and security purposes) and, unfortunately, matches well what the outsourcing industry can offer. We are training easily replaceable professionals.
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As faculty members at New York University for decades, we have regretted the introduction of Java as a first language of instruction for most computer science majors. We have seen how this choice has weakened the formation of our students, as reflected in their performance in systems and architecture courses.
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Every programmer must be comfortable with functional programming and with the important notion of referential transparency. Even though most programmers find imperative programming more intuitive, they must recognize that in many contexts that a functional, stateless style is clear, natural, easy to understand, and efficient to boot.

An additional benefit of the practice of Lisp is that the program is written in what amounts to abstract syntax, namely the internal representation that most compilers use between parsing and code generation. Knowing Lisp is thus an excellent preparation for any software work that involves language processing.

Dewar, a professor emeritus of computer science at New York University, believes that U.S. colleges are turning out programmers who are – there’s no nice way to say this – essentially incompetent.

The language of DNA is digital, but not binary. Where binary encoding has 0 and 1 to work with (2 - hence the ‘bi’nary), DNA has 4 positions, T, C, G and A. Whereas a digital byte is mostly 8 binary digits, a DNA ‘byte’ (called a ‘codon’) has three digits. Because each digit can have 4 values instead of 2, an DNA codon has 64 possible values, compared to a binary byte which has 256.

A typical example of a DNA codon is ‘GCC’, which encodes the amino acid Alanine. A larger number of these amino acids combined are called a ‘polypeptide’ or ‘protein’, and these are chemically active in making a living being.
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Furthermore, 97% of your DNA is commented out. DNA is linear and read from start to end. The parts that should not be decoded are marked very clearly, much like C comments. The 3% that is used directly form the so called ‘exons’. The comments, that come ‘inbetween’ are called ‘introns’.