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Correlation is not causation. And reporting of the form, “1 time this happened” and so I report it as though it is some relevant fact, is sad. Take any incident that happened and then state random traits you want to imply there is some relevant link to (blue eyes, red hair, people that watch IT Crowd, people that bought a banana yesterday, tall, overweight, did poorly in math…) and most people will know you are ignorant.
Looking at random data people will find patterns. Sound scientific experimentation is how we learn, not trying to find anything that support our opinions. Statistics don’t lie but ignorant people draw faulty conclusions from data (when they are innumerate - illiteracy with mathematical concepts).
It’s not what the papers say, it’s what they don’t by Ben Goldacre
On Thursday the coroner announced his verdict: the vaccine played no part in this child’s death. So far, of the papers above, only the Telegraph has had the decency to cover the outcome.
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Measles cases are rising. Middle class parents are not to blame, even if they do lack rhetorical panache when you try to have a discussion with them about it.
They have been systematically and vigorously misled by the media, the people with access to all the information, who still choose, collectively, between themselves, so robustly that it might almost be a conspiracy, to give you only half the facts.
Science education is important. Even if people do not become scientists, ignorance of scientific thinking is dangerous. The lack of scientific literacy allows scientifically illiterate leaders to make claims that are lacking scientific merit. And results in people making poor choices themselves, due to their ignorance.
Related: Bad Science blog by Ben Goldacre - Illusion of Explanatory Depth - Illusions - Optical and Other - posts on vaccines - posts on scientific literacy
Gene against bacterial attack unravelled
Wiersinga focussed on the so-called Toll-like receptors. These are the proteins that initiate the fight against pathogens. There are currently ten known Toll-like receptors which are located on the outside of immune cells, our body’s defence system. The toll-like receptors jointly function as a 10-figure alarm code. Upon coming into contact with the immune cell each bacterium enters its own Toll code. For known pathogens this sets off an alarm in the immune system and the defence mechanism is activated. Yet B. pseudomallei fools the system by entering the code of a harmless bacterium. As a result the body’s defence system remains on standby.
Yet some people are resistant: they become infected but not ill. Wiersinga found a genetic cause for this resistance. He discovered which toll receptor can fend off B. pseudomallei. He did this by rearing mice DNA in which the gene for Toll2 production was switched on and off. ‘The group where the gene for Toll2 was switched off, survived the bacterial infection’, says Wiersinga. ‘The other receptor that we investigated, Toll4, had no effect - even though for the past ten years medics had regarded this as the most important receptor.’ The ultimate aim of this study is to develop a vaccine.
PLoS paper: MyD88 Dependent Signaling Contributes to Protective Host Defense against Burkholderia pseudomallei
Related: Bacteria Can Transfer Genes to Other Bacteria - Disrupting the Replication of Bacteria - Amazing Designs of Life - posts on medical research
Do Flu Shots For The Elderly Save Lives? Just Washing Hands Works Better, Says Study
The study included more than 700 matched elderly subjects, half of whom had taken the vaccine and half of whom had not. After controlling for a wealth of variables that were largely not considered or simply not available in previous studies that reported the mortality benefit, the researchers concluded that any such benefit “if present at all, was very small and statistically non-significant and may simply be a healthy-user artifact that they were unable to identify.”
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“Over the last two decades in the United Sates, even while vaccination rates among the elderly have increased from 15 to 65 percent, there has been no commensurate decrease in hospital admissions or all-cause mortality
Related: New and Old Ways to Make Flu Vaccines - Study Shows Why the Flu Likes Winter - Over-reliance on Prescription Drugs to Aid Children’s Sleep?
Science Tuesday: Back into the hornets nest is a thoughtful follow-up post on the decision of a scientist to vaccinate his child.
This is one of the examples of what is so good about blogs. Great content that probably would not be available but through a blog.
Related: Scientists Reconsider Autism - Autism, Science and Politics - posts on vaccination
Clinton and Obama parrot the “vaccine and autism connection inconclusive” line by Tara C. Smith:
The National Children’s Study will examine the effects of environmental influences on the health and development of more than 100,000 children across the United States, following them from before birth until age 21. The goal of the study is to improve the health and well-being of children.
Variables examined will include vaccinations received, and development of autism will be one of the outcomes examined. What more can you ask for? Obama and Clinton’s claims of ignorance on the part of the scientific community when it comes to vaccines and autism show that we don’t have any real science defenders in the running.
Related: Scientists and Engineers in Congress - Science and Engineering in Politics - The A to Z Guide to Political Interference in Science
Engineered Protein Shows Potential as a Strep Vaccine
Related: New and Old Ways to Make Flu Vaccines - MRSA Vaccine Shows Promise - New Approach Builds Better Proteins Inside a Computer
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