Currently browsing the quote Category

Mainly I tag posts I think I will want to find easily. But this might also provide an interesting collection to browse for visitors.
Recommended posts: What Kids can Learn - Engineering the Economy - USA Under-counting Engineering Graduates - Children’s view of Scientists in England - Economics, Politics and Science Research - Phony Science Gap? - Questioning the Accuracy of Scientific Papers

Healthy Diet, Healthy Living, Healthy Weight

Living and eating healthily is tricky but not entirely confusing. The whole area of eating healthy food and what is a healthy weight is one where the scientific inquiry process and the complexity of scientific research on what is healthy for us is clear. Scientists study various issues and learn things but creating simple rules has proven difficult. Different studies seem to show benefits of contradictory advice, advice once seen as wise is now seen as wrong…

This is an area I am far from knowledgable about. Still I try to pay some attention as I like being healthy. Being sick is the quickest way to appreciate how great it is to be healthy. From various things I have skimmed it seems there is more evidence from several studies about how difficult it is to lose weight. Our bodies seem to work against our efforts.

And this, it seems to me, makes the problem of increasing childhood and teen obesity even more important to deal with as soon as issues arise.

It seems to me the most important thing to take from this, is the importance of maintaining a healthy weight: since you can’t just easily make up for a bad year of weight gain. I am not sure why I haven’t seen this note in most of what I have read – I suspect it is our reluctance to make value judgements about what is healthy. The problem I see with that is, the best advice we have is confusing enough without people with more knowledge being reluctant to state their best advice given the current knowledge. That doesn’t mean the suggestions are right, but at least they are educated guesses.

I try to eat relatively healthily. Which for me means taking steps to increase the amount of vegetables I eat (especially greens and some fiber) and decrease the amount of sweets and heavily processed food I eat (I still eat way too much heavily processed food). And I try to exercise as it seems to have many benefits including helping make up for some weaknesses in your diet (like eating too many calories and too many “empty calories). In my opinion (which on this topic may well not be worth much) eating a bit more stuff that really isn’t so good for you and exercising more is an easier tradeoff than trying to eat perfectly and do the minimum amount of exercise needed to stay healthy.

I also eat yogurt – I like it and the beneficial benefits of some bacteria seems likely. I heard recently something that surprised me which is that the beneficial bacteria remain for close to 2 weeks. I figured they would be gone in a couple days. I only heard that from one source (I can’t remember now but some seemingly knowledgable source – scientist researching the area), so it might not be accurate but it was interesting.

Here is an example of one of these health studies. They find that a low protein diet resulted in a loss of “lean weight” (muscle…) and more fat than a comparable diet with more protein. The same weight with a higher percentage of fat is not a good thing for human health. Thus the message is that a lower protein diet has this risk that must be considered (and therefor higher protein diets may well be wise). Of course things get much more complicated than that when we actually try to live by a diet.

Effect of Dietary Protein Content on Weight Gain, Energy Expenditure, and Body Composition During Overeating

Continue reading

Nature Uses Stem Cells from Fetus to Repair Health of Mother

Science shows us so many amazing things. Scientists have learned mice use stem cells from the fetus to repair damage to the mother in the event of things like heart attacks. And there is evidence people do the same thing. Very cool. Nature beat us to the idea of using stem cells to treat health problems.

Helpful Mouse Fetuses Naturally Send Stem Cells to Mom to Fix Her Damaged Heart

When the scientists examined the female mice’s heart tissue two weeks after the heart attacks, they found lots of glowing green tissue—cells that came from the fetus—in the mom’s heart. Mice who had heart attacks had eight times as many cells from the fetus in their hearts as mice who hadn’t had a heart attack did, meaning the high volume of fetal cells was a response to the heart attack.

What’s more, the embryo’s stem cells had differentiated into various types of heart tissue, including cardiomyocytes, the rhythmically contracting muscle cells that produce a heartbeat.

The hearts of two women who suffered from severe heart weakness were later found to contain cells derived from the cells of a male fetus years after they gave birth to their sons.

The same thing seems to hold true for other organs. When pregnant women have damage in other organs, including the brain, lung, and liver, earlier studies have shown, fetal cells show up there, too.

It makes sense for a fetus to try and aid the mother but it is amazing the evolution found such solutions. Given how many challenges the fetus creates for the mother giving some benefits can help increase the odds of a health birth.

Related: Researchers Explain How Rotifers Thrive Despite Forgoing SexMaking Embryonic Stem CellsStructure and Function of RibosomeWhy People Often Get Sicker When They’re Stressed

Encouraging Curiosity in Kids

How do you help make your children scientifically literate? I think the biggest thing you can do is encourage curiosity.

One way to encourage curiosity it is by answering their questions (and not saying: I am too busy, don’t bother me, don’t ask me?, stop asking why…). I know adults are busy and have all sorts of stuff we are trying to get done; and the question about why I need to wash my hands doesn’t seem worth answering. But I think anytime a kid is asking why is an opportunity to teach and encourage them to keep being curious.

It is very easy to shut off this curiosity, in our society anyway (we do it to the vast majority of people). The biggest difference I see between adults and kids is not maturity or responsibility but curiosity (or lack thereof in adults) and joy (versus adults who seem to be on valium all the time – maybe they are).

As they grow up kids will have lots of science and technology questions that you don’t know the answers to. If you want them to be curious and knowledgeable, put in the effort to find answers with them. You have to help them find the answers in a way that doesn’t turn them off. If you just say – go look it up yourself (which really they can do), maybe the 2% that are going to become scientists will. But most kids will just give up and turn off their curiosity a little bit more (until eventually it is almost gone and they are ready to fit into the adult world). Which is very sad.

Once you get them used to thinking and looking things up they will start to do this on their own. A lot of this just requires thinking (no need to look things up – once a certain base knowledge is achieved). But you need to set that pattern. And it would help if you were curious, thought and learned yourself.

Photo of kids intently studying on a Malaysian beach

My mom with a group of Malaysia kids apparently intent on learning something. I am there, but not visible in this photo. Photo by my father.

While walking in the park, see one of those things you are curious about and ask why does…? It is good to ask kids why and let them think about it and try and answer. Get them in the habit of asking why themselves. And in those cases when no-one knows, take some time and figure it out. Ask some questions (both for yourself – to guide your thinking – and to illustrate how to think about the question and figure things out). If you all can’t find an explanation yourselves, take some time to look it up. Then at dinner, tell everyone what you learned. This will be much more interesting to the kids than forcing them to elaborate on what they did today and help set the idea that curiosity is good and finding explanations is interesting.

It is fun as a kid if your parent is a scientist or engineer (my father was an engineering professor).

You often don’t notice traits about yourself. In the same what I know what red looks like to me, I figure we both see this red shirt you see the red that I do. But maybe you don’t. I tend to constantly be asking myself why. If I see something new (which is many, many times a day – unless I am trapped in some sad treadmill of sameness) I ask why is it that way and then try and answer. I think most of this goes on subconsciously or some barely conscious way. I actually had an example a few months ago when I was visiting home with my brother (who is pretty similar to me).

As we were driving, I had noticed some fairly tall poles that seemed to have really small solar panels on top. I then noticed they were space maybe 20 meters apart. Then saw that there seemed to be a asphalt path along the same line. I then decided, ok, they are probably solar panels to power a light for the path at night. Then my brother asked why are there those small solar panel on top of that pole?

Continue reading

Career Prospect for Engineers Continues to Look Positive

As I have written previously the career prospects for engineers are bright around the globe. Many countries realize the importance of engineering and have taken steps to compete as a center of excellence for engineering. It is a smart economic policy. Ironically, the USA, that did such a great job at this in the 1960′s and 1970′s, has been falling down in this regard. A significant reason for this is the USA can only fund so many things and a broken health care system, military complex, bailouts to bankers (trust fund babies and others) cost a lot of money. You chose what to fund, and those are taking much of the available USA funds. There are also non-economic reasons, such as the turn in the last decade in the USA to make the barriers for foreigner engineers (and others) to go through to go to school, visit and stay in the USA have all increased dramatically.

Back to the prospects for engineers: their are shortages of good engineers all over (and the future projections don’t show any reason to believe this will change). Germany Faces a Shortage of Engineers:

In June, the Association of German Engineers (VDI) reported that there were 76 400 vacant engineering jobs—an all-time high.

Policymakers in Berlin have responded to the shortage of skilled workers with a number of measures, including changes in immigration rules that allow German companies to hire engineers from other countries, including those outside of the European Union. Among them: The annual salary that companies must pay foreigners has been lowered from 60,000 Euro (US $95,000) to 40,000 Euro, which is roughly the starting salary of an engineering graduate in Germany…

To make it easy for engineers to move around Europe, engineering associations and other groups across Europe are working with the European Commission (the executive arm of the European Union) to launch the new Engineering Card. The card, which German engineers can apply for now and other countries are planning to launch, provides standardized information about the engineer’s qualifications and skills for greater transparency.

“We don’t expect many engineers will come, because among other reasons, there is a shortage of engineers across Europe,”

Related: Engineering Again Dominates The Highest Paying College Degree ProgramsS&P 500 CEO’s: Engineers Stay at the TopChina’s Technology Savvy LeadershipEngineers: Future ProspectsEconomic Strength Through Technology Leadership

Continue reading

Cancer Vaccines

A reader commented on a previous post (MIT Engineers Design New Type of Nanoparticle for Vacines) asking about how vaccines can fight cancer. Preventative vaccines can build up immune response to viruses which cause cancer. So the vaccine actually works against the virus which prevents the virus from causing cancer.

The U.S. Food and Drug Administration (FDA) has approved two vaccines, Gardasil® and Cervarix®, that protect against infection by the two types of human papillomavirus (HPV) – types 16 and 18 – that cause approximately 70% of all cases of cervical cancer worldwide. At least 17 other types of HPV are responsible for the remaining 30% of cervical cancer cases. HPV types 16 and/or 18 also cause some vaginal, vulvar, anal, penile, and oropharyngeal cancers.

Many scientists believe that microbes cause or contribute to between 15% and 25% of all cancers diagnosed worldwide each year, with the percentages being lower in developed than developing countries.

Vaccines can also help stimulate the immune system to fight cancers.

B cells make antibodies, which are large secreted proteins that bind to, inactivate, and help destroy foreign invaders or abnormal cells. Most preventive vaccines, including those aimed at hepatitis B virus (HBV) and human papillomavirus (HPV), stimulate the production of antibodies that bind to specific, targeted microbes and block their ability to cause infection. Cytotoxic T cells, which are also known as killer T cells, kill infected or abnormal cells by releasing toxic chemicals or by prompting the cells to self-destruct (a process known as apoptosis).

Other types of lymphocytes and leukocytes play supporting roles to ensure that B cells and killer T cells do their jobs effectively. These supporting cells include helper T cells and dendritic cells, which help activate killer T cells and enable them to recognize specific threats.

Cancer treatment vaccines are designed to work by activating B cells and killer T cells and directing them to recognize and act against specific types of cancer. They do this by introducing one or more molecules known as antigens into the body, usually by injection. An antigen is a substance that stimulates a specific immune response. An antigen can be a protein or another type of molecule found on the surface of or inside a cell.

Related: National Cancer Institute (USA)Nanoparticles With Scorpion Venom Slow Cancer SpreadUsing Bacteria to Carry Nanoparticles Into CellsGlobal Cancer Deaths to Double by 2030
Continue reading

Vaccines Can’t Provide Miraculous Results if We Don’t Take Them

Vaccine preventable diseases used to ravage our health. In the USA, we are lucky to live in a society where those before us have taken vaccines and reduced to very low levels the attack vectors for these diseases. If nearly everyone is vaccinated for polio, even if it crops up with one person, most likely it won’t spread. As more people chose to risk the health of others in the society by failing to vaccinate, an infection can spread rapidly. There are some people who can’t be vaccinated for one reason or another (normally dangerous allergies) and vaccines, while very effective are not 100% effective. So any person that fails to vaccinate their kids endangers society and those who cannot be vaccinated.

Six Top Vaccine Myths

Myth 1: It’s not necessary to vaccinate kids against diseases that have been largely eradicated in the United States.
Reality: Although some diseases like polio and diphtheria aren’t often seen in America (in large part because of the success of the vaccination efforts), they can be quite common in other parts of the world. The Centers for Disease Control and Prevention warns that travelers can unknowingly bring these diseases into the United States, and if we were not protected by vaccinations, these diseases could quickly spread throughout the population. At the same time, the relatively few cases currently in the U.S. could very quickly become tens or hundreds of thousands of cases without the protection we get from vaccines. Brown warns that these diseases haven’t disappeared, “they are merely smoldering under the surface.”

Most parents do follow government recommendations: U.S. national immunization rates are high, ranging from 85 percent to 93 percent, depending on the vaccine, according to the CDC.

See the 2010 Child & Adolescent Immunization Schedules from the CDC and protect your children and society. The suffering caused by preventable diseases like polio and small pox was huge. We should not delude ourselves into thinking that those diseases are not dangerous. They are. We have been protected by all those taking vaccines. If people in the society don’t take vaccines that increases the health risks to the society at large.

Routine smallpox vaccination among the American public stopped in 1972 after the disease was eradicated in the United States. The United States government has enough vaccine to vaccinate every person in the United States in the event of a smallpox emergency (mainly due to concerns about bio-terrorism).

U.S. Adults Dying of Preventable Diseases

Diseases easily preventable by adult vaccines kill more Americans each year than car wrecks, breast cancer, or AIDS.

“We have a chronic disease epidemic in the U.S. It is taxing our families and taxing our economy,” the CDC’s Anne Schuchat, MD, said at the news conference. “We have a need for culture change in America. We worry about things when they are really bad rather than focusing on prevention, which can keep us out of the hospital and keep our families thriving.”

In other parts of the world the danger is not from those who chose not to vaccinate their children but those who are not provided the opportunity to.

Bill Gates’ war on disease, poverty is an uphill battle
Continue reading

Teaching Through Tinkering

I wrote about the Tinkering School, Engineering camp previously. I am a strong believer in the value of helping kids (even adult kids – the few that haven’t resigned themselves to limited capacity to wonder since they now are grown up and not suppose to waste their time dreaming) explore their ideas and assisting them in making those ideas into reality. I think this is the best way to learn, not learning to pass a test, but learning to gain knowledge and accomplish things. Here is a nice 15 minute talk by the founder of the Tinkering School, Gever Tulley: “Turning Curriculum Design On Its Head: Engage First Then Look for Learning Within”

The format of the tinkering school is week long sessions where the kids stay overnight.

Some quotes: “we would use real tools and real materials and we would build real things, not model building, [but instead] actual building.” “create a meaningful experience and learning will follow”

Gever Tulley recently published: Fifty Dangerous Things (You Should Let Your Children Do).

Related: Home Engineering: Building a HovercraftKids Need Adventurous PlayAutomatic Cat FeederScience Toys You Can Make With Your KidsWhat Kids can Learn

Trying to Find Pest Solutions While Hoping Evolution Doesn’t Exist Doesn’t Work

How To Make A Superweed

Melander wondered why some populations of scales were becoming able to resist pesticides. Could the sulfur-lime spray trigger a change in their biology, the way manual labor triggers the growth of callouses on our hands? Melander doubted it. After all, ten generations of scales lived and died between sprayings. The resistance must be hereditary, he reasoned. He sometimes would find families of scales still alive amidst a crowd of dead insects.

This was a radical idea at the time. Biologists had only recently rediscovered Mendel’s laws of heredity. They talked about genes being passed down from one generation to the next, yet they didn’t know what genes were made of yet. But they did recognize that genes could spontaneously change–mutate–and in so doing alter traits permanently.

In the short term, Melander suggested that farmers switch to fuel oil to fight scales, but he warned that they would eventually become resistant to fuel oil as well. In fact, the best way to keep the scales from becoming entirely resistant to pesticides was, paradoxically, to do a bad job of applying those herbicides. By allowing some susceptible scales to survive, farmers would keep their susceptible genes in the scale population. “Thus we may make the strange assertion that the more faulty the spraying this year the easier it will be to control the scale the next year,” Melander predicted.

What’s striking is how many different ways weeds have found to overcome the chemical. Scientists had thought that Roundup was invincible in part because the enzyme it attacks is pretty much the same in all plants. That uniformity suggests that plants can’t tolerate mutations to it; mutations must change its shape so that it doesn’t work and the plant dies. But it turns out that many populations of ryegrass and goosegrass have independently stumbled across one mutation that can change a single amino acid in the enzyme. The plant can still survive with this altered enzyme. And Roundup has a hard time attacking it thanks to its different shape.

Another way weeds fight off Roundup is through sheer numbers. Earlier this year an international team of scientists reported their discovery of how Palmer amaranth resists glyphosate. The plants make the ordinary, vulnerable form of the enzyme. But the scientists discovered that they have many extra copies of the gene for the enzyme–up to 160 extra copies, in fact.

What makes the evolution of Roundup resistance all the more dangerous is how it doesn’t respect species barriers. Scientists have found evidence that once one species evolves resistance, it can pass on those resistance genes to other species. They just interbreed, producing hybrids that can then breed with the vulnerable parent species.

Another great article from Carl Zimmer.

Related: Amazing Designs of LifeMicrocosm by Carl ZimmerParasite RexPigs Instead of Pesticides

Poor Results on Evolution and Big Bang Questions Omitted From NSF Report

Evolution, Big Bang Polls Omitted From NSF Report by Yudhijit Bhattacharjee

The section, which was part of the unedited chapter on public attitudes toward science and technology, notes that 45% of Americans in 2008 answered true to the statement, “Human beings, as we know them today, developed from earlier species of animals.” The figure is similar to previous years and much lower than in Japan (78%), Europe (70%), China (69%), and South Korea (64%). The same gap exists for the response to a second statement, “The universe began with a big explosion,” with which only 33% of Americans agreed.

The USA continues to lag far behind the rest of the world in this basic science understanding. Similar to how we lag in other science and mathematical education. Nearly Half of Adults in the USA Don’t Know How Long it Takes the Earth to Circle the Sun.

Jon Miller, a science literacy researcher at Michigan State University in East Lansing who authored the survey 3 decades ago and conducted it for NSF until 2001. “Evolution and the big bang are not a matter of opinion. If a person says that the earth really is at the center of the universe, even if scientists think it is not, how in the world would you call that person scientifically literate? Part of being literate is to both understand and accept scientific constructs.”

I completely agree. People have the right to their opinions. But those opinions which are related to scientific knowledge (whether it is about evolution, the origin of the universe, cancer, the speed of light, polio vaccinations, multi-factorial designed experiments, magnetic fields, chemical catalysts, the effectiveness of antibiotics against viral infections, electricity, optics, bioaccumulation, etc.) are part of their scientific literacy. You can certainly believe antibiotics are affective against viral infections but that is an indication you are scientifically illiterate on that topic.

2006 NSF chapter that included the results
Continue reading

Why Wasn’t the Earth Covered in Ice 4 Billion Years Ago – When the Sun was Dimmer

Climate scientists from all over the globe are now able to test their climate models under extreme conditions thanks to Professor Minik Rosing, University of Copenhagen. Rosing has solved one of the great mysteries and paradoxes of our geological past, namely, “Why the earth’s surface was not just one big lump of ice four billion years ago when the Sun’s radiation was much weaker than it is today.” Until now, scientists have presumed that the earth’s atmosphere back then consisted of 30% carbon dioxide (CO2) which ensconced the planet in a protective membrane, thereby trapping heat like a greenhouse.

The faint early sun paradox
In 1972, the late, world famous astronomer Carl Sagan and his colleague George Mullen formulated “The faint early sun paradox. ” The paradox consisted in that the earth’s climate has been fairly constant during almost four of the four and a half billion years that the planet has been in existence, and this despite the fact that radiation from the sun has increased by 25-30 percent.

The paradoxical question that arose for scientists in this connection was why the earth’s surface at its fragile beginning was not covered by ice, seeing that the sun’s rays were much fainter than they are today. Science found one probable answer in 1993, which was proffered by the American atmospheric scientist, Jim Kasting. He performed theoretical calculations that showed that 30% of the earth’s atmosphere four billion years ago consisted of CO2. This in turn entailed that the large amount of greenhouse gases layered themselves as a protective greenhouse around the planet, thereby preventing the oceans from freezing over.

Mystery solved
Now, however, Professor Minik Rosing, from the Natural History Museum of Denmark, and Christian Bjerrum, from the Department of Geography and Geology at University of Copenhagen, together with American colleagues from Stanford University in California have discovered the reason for “the missing ice age” back then, thereby solving the sun paradox, which has haunted scientific circles for more than forty years.

Professor Minik Rosing explains, “What prevented an ice age back then was not high CO2 concentration in the atmosphere, but the fact that the cloud layer was much thinner than it is today. In addition to this, the earth’s surface was covered by water. This meant that the sun’s rays could warm the oceans unobstructed, which in turn could layer the heat, thereby preventing the earth’s watery surface from freezing into ice. The reason for the lack of clouds back in earth’s childhood can be explained by the process by which clouds form. This process requires chemical substances that are produced by algae and plants, which did not exist at the time. These chemical processes would have been able to form a dense layer of clouds, which in turn would have reflected the sun’s rays, throwing them back into the cosmos and thereby preventing the warming of earth’s oceans. Scientists have formerly used the relationship between the radiation from the sun and earth’s surface temperature to calculate that earth ought to have been in a deep freeze during three billion of its four and a half billion years of existence. Sagan and Mullen brought attention to the paradox between these theoretical calculations and geological reality by the fact that the oceans had not frozen. This paradox of having a faint sun and ice-free oceans has now been solved.”

CO2 history iluminated
Minik Rosing and his team have by analyzing samples of 3.8-billion-year-old mountain rock from the world’s oldest bedrock, Isua, in western Greenland, solved the “paradox”.

But more importantly, the analyses also provided a finding for a highly important issue in today’s climate research – and climate debate, not least: whether the atmosphere’s CO2 concentration throughout earth’s history has fluctuated strongly or been fairly stable over the course of billions of years.

“The analyses of the CO2-content in the atmosphere, which can be deduced from the age-old Isua rock, show that the atmosphere at the time contained a maximum of one part per thousand of this greenhouse gas. This was three to four times more than the atmosphere’s CO2-content today. However, not anywhere in the range of the of the 30 percent share in early earth history, which has hitherto been the theoretical calculation. Hence we may conclude that the atmosphere’s CO2-content has not changed substantially through the billions of years of earth’s geological history. However, today the graph is turning upward. Not least due to the emissions from fossil fuels used by humans. Therefore it is vital to determine the geological and atmospheric premises for the prehistoric past in order to understand the present, not to mention the future, in what pertains to the design of climate models and calculations,” underscores Minik Rosing.

Full press release from the University of Copenhagen in Denmark.

Related: Sun Missing It’s SpotsSolar StormsWhy is it Colder at Higher Elevations?Magnetic Portals Connect Sun and Earth

Statistical Errors in Medical Studies

I have written about statistics, and various traps people often fall into when examining data before (Statistics Insights for Scientists and Engineers, Data Can’t Lie – But People Can be Fooled, Correlation is Not Causation, Simpson’s Paradox). And also have posted about reasons for systemic reasons for medical studies presenting misleading results (Why Most Published Research Findings Are False, How to Deal with False Research Findings, Medical Study Integrity (or Lack Thereof), Surprising New Diabetes Data). This post collects some discussion on the topic from several blogs and studies.

HIV Vaccines, p values, and Proof by David Rind

if vaccine were no better than placebo we would expect to see a difference as large or larger than the one seen in this trial only 4 in 100 times. This is distinctly different from saying that there is a 96% chance that this result is correct, which is how many people wrongly interpret such a p value.

So, the modestly positive result found in the trial must be weighed against our prior belief that such a vaccine would fail. Had the vaccine been dramatically protective, giving us much stronger evidence of efficacy, our prior doubts would be more likely to give way in the face of high quality evidence of benefit.

While the actual analysis the investigators decided to make primary would be completely appropriate had it been specified up front, it now suffers under the concern of showing marginal significance after three bites at the statistical apple; these three bites have to adversely affect our belief in the importance of that p value. And, it’s not so obvious why they would have reported this result rather than excluding those 7 patients from the per protocol analysis and making that the primary analysis; there might have been yet a fourth analysis that could have been reported had it shown that all important p value below 0.05.

How to Avoid Commonly Encountered Limitations of Published Clinical Trials by Sanjay Kaul, MD and and George A. Diamond, MD

Trials often employ composite end points that, although they enable assessment of nonfatal events and improve trial efficiency and statistical precision, entail a number of shortcomings that can potentially undermine the scientific validity of the conclusions drawn from these trials. Finally, clinical trials often employ extensive subgroup analysis. However, lack of attention to proper methods can lead to chance findings that might misinform research and result in suboptimal practice.

Why Most Published Research Findings Are False by John P. A. Ioannidis
Continue reading

  • Recent Comments:

    • Donnie: Hong Kong is a city in China…… The stupidity of my country continues to amaze me.
    • Igoritza: Damn, Abel … where did you get that one from .. ? I would like to see extended theory of Dr...
    • curiouscat: I agree that ADHD medication is warranted in some cases. My guess is that is much much lower...
    • Tom Bargeron: I know that there is tendency for over active kids especially boys to be diagnosed as having...
    • sojib: wow Magnetic Movie is so amazing . I don’t think about that how can it’s making for...
    • Vance Miller: I can’t get enough vegetables, even when I try. I have made it a priority to go to our...
    • marylou: I’m agree. I’ve been friendless for 2 years and my BF said I’m more stone...
    • marylou: what a terrible myth it is those wannabe experts spread that if you want to lose weight, you have...
  • Recent Trackbacks:

  • Links