Scientific inquiry is aided by sensible application of statistical tools. I grew up around the best minds in applied statistics. My father was an eminent applied statistican, and George Box (the person in the video) was often around our house (or we were at his). Together they wrote Statistics for Experimenters (along with Stu Hunter, not related to me) the bible for design of experiments (George holds up the 1st edition in the video).
The video may be a bit confusing without at least a basic idea of factorial designed experiments. These introductory videos, by Stu Hunter, on Using Design of Experiments to Improve Results may help get you up to speed.
This video looks at using fractional factorials to reduce the number of experiments needed when doing a multifactor experiment. I grew up understanding that the best way to experiment is by varying multiple factors at the same time. You learn much quicker than One Factor At a Time (OFAT), and you learn about interactions (which are mainly lost in OFAT). I am amazed to still hear scientists and engineers talk about OFAT as a sensible method or even as the required method, but I know many do think that way.
To capture the interactions a full factorial requires an ever larger number of experimental runs to be complete. Assessing 4 factors requires 16 runs, 6 would require 64 and 8 would require 256. This can be expensive and time consuming. Obviously one method is to reduce the number of factors to experiment with. That is done (by having those knowledgable about the process include only those factors worth the effort), but if you still have, for example, 8 very important factors using a fractional factorial design can be very helpful.
And as George Box says “What you will often find is that there will be redundant factors… and don’t forget about those redundant factors. Knowing that something doesn’t matter is almost as important as knowing what does.” If you learn a factor isn’t having an affect you may be able to save money. And you can eliminate varying that factor in future experiments.



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George Box 1919 to 2013 – A Great Friend, Scientist and Statistician
Posted on March 30, 2013 Comments (2)
Reposted from my management blog.
I would most likely not exist if it were not for George Box. My father took a course from George while my father was a student at Princeton. George agreed to start the Statistics Department at the University of Wisconsin – Madison, and my father followed him to Madison, to be the first PhD student. Dad graduated, and the next year was a professor there, where he and George remained for the rest of their careers.
George died today, he was born in 1919. He recently completed An Accidental Statistician: The Life and Memories of George E. P. Box which is an excellent book that captures his great ability to tell stories. It is a wonderful read for anyone interested in statistics and management improvement or just great stories of an interesting life.
George Box by Brent Nicastro.
George Box was a fantastic statistician. I am not the person to judge, but from what I have read one of the handful of most important applied statisticians of the last 100 years. His contributions are enormous. Several well know statistical methods are known by his name, including:
George was elected a member of the American Academy of Arts and Sciences in 1974 and a Fellow of the Royal Society in 1979. He also served as president of the American Statistics Association in 1978. George is also an honorary member of ASQ.
George was a very kind, caring and fun person. He was a gifted storyteller and writer. He had the ability to present ideas so they were easy to comprehend and appreciate. While his writing was great, seeing him in person added so much more. Growing up I was able to enjoy his stories often, at our house or his. The last time I was in Madison, my brother and I visited with him and again listened to his marvelous stories about Carl Pearson, Ronald Fisher and so much more. He was one those special people that made you very happy whenever you were near him.
George Box, Stuart Hunter and Bill Hunter (my father) wrote what has become a classic text for experimenters in scientific and business circles, Statistics for Experimenters. I am biased but I think this is acknowledged as one of (if not the) most important books on design of experiments.
George also wrote other classic books: Time series analysis: Forecasting and control (1979, with Gwilym Jenkins) and Bayesian inference in statistical analysis. (1973, with George C. Tiao).
George Box and Bill Hunter co-founded the Center for Quality and Productivity Improvement at the University of Wisconsin-Madison in 1984. The Center develops, advances and communicates quality improvement methods and ideas.
The Box Medal for Outstanding Contributions to Industrial Statistics recognizes development and the application of statistical methods in European business and industry in his honor.
“All models are wrong but some are useful” is likely his most famous quote. More quotes By George Box
A few selected articles and reports by George Box
Related: It is not about proving a theorem it is about being curious about things – Box on Quality – Soren Bisgaard – Learning Design of Experiments with Paper Helicopters – Peter Scholtes
Categories: Engineering
Tags: books, commentary, data, design of experiments, experiment, John Hunter, learning, Madison, quote, Science, scientists, statistics