One of your first “Stuff Happens” episodes is about breakfast. What’s so special about breakfast and the environment?
Are you kidding? It’s the most important meal of the day. It had the iconic story that North American pigs - from where we get bacon - I presume unwillingly are fed feed made with South American anchovies (and herrings and sardines). Farmers say eating fish helps their animals grow to that wonderfully ample size consumers want. Because of this, we’re accidentally destroying an ecosystem. It’s the story of stories.

How so?
We’re seriously depleting the world’s anchovy population and leaving the penguins and South American seabirds with nothing to eat. These birds are dangerously close to starving because the anchovy and sardine populations have been decimated.

What can we do?
Strange as it may seem, you could eat more anchovies. This would raise the price of the fish and make anchovy fish feed more costly and less desirable to pig farmers. Also eat organic bacon from pigs raised on 100% agricultural feed. If you’re looking for the true organic meat products, make sure it’s grass-fed only.

Autism isn’t like tuberculosis, there’s not a bacteria that causes the disease. In fact,most researchers believe that “autism” is not a discrete disorder, rather “autism is a clinically defined pervasive developmental disorder with phenotypically diverse neuropsychiatric symptoms and characteristics. These manifest as a spectrum of social and communicative deficits, stereotypical patterns and disturbances of behaviour.”¹
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If a particular trait’s heritability is 100% then the trait is due entirely to genetic variation, if the heritability is 0% then the trait is due entirely to environmental variation. By some estimates, heritability of autism spectrum disorders exceeds 90%
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repeated studies have found that autism diagnoses continue to rise even after the removal of thimerosal from the vaccine.
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Finally, when thinking about the environmental influences on autism, it’s important to explore the role of the environment on genetics. Many of the types of genetic changes that have been identified as causative in autism are indicative of some sort of DNA damage - DNA damage that may result from exposure to an environmental toxin. Many scientists, and I count myself in their number, feel that the recent autism ‘epidemic’ is due primarily to improved screening and diagnosis. In other words, prior to the 1980’s, many people suffering from autism were diagnosed as “slow” or misdiagnosed with another type of mental retardation. Unfortunately, there is no way to quantify this hypothesis.

Well, no kidding. I’m 3000 miles from my old stomping grounds. I’m trying to start an independent research program in a place where the geology/climate are not at all the same. I’m applying for $ for that are specific to Mystery State. Damn straight I’m going to need to learn a few new techniques. (And we’re not talking rocket science here.) But was there nothing in the proposal to suggest that I didn’t understand the techniques or wasn’t properly applying them. Just a lack of a publication record that explicitly used those techniques or occurred in this part of the country.

I suspect that this is a criticism that I’m going to see a few more times before tenure. And I suspect that it’s a criticism that’s not uniquely being leveled at me.
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In this case, this criticism isn’t the reason the proposal wasn’t funded. But it’s the one reviewer critique that I can’t surmount on the resubmission. It’s like that itch I can’t scratch. So I guess the resubmitted proposal is just going to have to be so kick-ass in all other respects that there’s no way they can deny me these funds. Better get to work.

Heisenberg set himself the task of finding the new quantum mechanics upon returning to Göttingen from Copenhagen in April 1925. Inspired by Bohr and his assistant, H.A. Kramers, in Copenhagen, Pauli in Hamburg, and Born in Göttingen, Heisenberg’s intensive struggle over the following months to achieve his goal has been well documented by historians. Since the electron orbits in atoms could not be observed, Heisenberg tried to develop a quantum mechanics without them.

He relied instead on what can be observed, namely the light emitted and absorbed by the atoms. By July 1925 Heisenberg had an answer, but the mathematics was so unfamiliar that he was not sure if it made any sense. Heisenberg handed a paper on the derivation to his mentor, Max Born, before leaving on a month-long lecture trip to Holland and England and a camping trip to Scandinavia with his youth-movement group. After puzzling over the derivation, Born finally recognized that the unfamiliar mathematics was related to the mathematics of arrays of numbers known as “matrices.” Born sent Heisenberg’s paper off for publication. It was the breakthrough to quantum mechanics.

His exposure to polymer science led him to pursue a Ph.D. in chemistry from Virginia Polytechnic Institute and State University in Blacksburg, Va. At the age of 25, DeSimone joined the University of North Carolina at Chapel Hill (UNC) as an assistant professor in chemistry and launched the university’s polymer program with his mentor Dr. Edward Samulski. He resides there today as the Chancellor’s Eminent Professor of Chemistry at UNC, in addition to serving as the William R. Kenan, Jr. Distinguished Professor of Chemical Engineering at North Carolina State University.

Among DeSimone’s notable inventions is an environmentally friendly manufacturing process that relies on supercritical carbon dioxide instead of water and bio-persistent surfactants (detergents) for the creation of fluoropolymers or high-performance plastics, such as Teflon®. More recently, he worked on a team to design a polymer-based, fully bioabsorbable, drug-eluting stent, which helps keep a blocked blood vessel open after a balloon-angioplasty and is absorbed by the body within 18 months.

DeSimone’s newest invention is PRINT® (Particle Replication in Non-wetting Templates) technology, used to manufacture nanocarriers in medicine. At present, DeSimone’s Lab is vested in a variety of projects that also extend beyond medicine, including potential applications for more efficient solar cells and morphable robots. In 2004, DeSimone co-founded Liquidia Technologies with a team of researchers from UNC to make the technology available in the market. Liquidia is using the PRINT technology to develop precisely engineered nanocarriers for highly targeted delivery of biological and small molecule therapeutics to treat cancer and other diseases. DeSimone’s proposed applications for cancer treatment with the PRINT platform was instrumental in UNC landing a grant of $24 million from the National Cancer Institute to establish the Carolina Center for Cancer Nanotechnology Excellence.

“You can do all the innovating you want in the laboratory, but if you can’t get it out of the university walls you do no one any good,” said DeSimone. He instills an entrepreneurial spirit in his students that focuses on the importance of commercializing technology and scientific inventions. One of DeSimone’s greatest accomplishments is his mentorship of more than 45 postdoctoral research associates, 52 Ph.D. candidates, six M.S. theses and 21 undergraduate researchers. Furthermore, he speaks to groups of high school students about the inventive process and encourages them to learn and explore areas that are less familiar to them to broaden their exposure to other disciplines.

A prolific inventor, DeSimone holds more than 115 issued patents with more than 70 new patent applications pending, and he has published more than 240 peer-reviewed scientific articles.

The answer, they say, cannot lie solely in the latest high-tech swimsuits introduced amid a swirl of controversy this winter, because the world-record smashing began at last year’s world championships — long before the newest of the newfangled apparel came out.

Swimmers, coaches and scientists say it is impossible to pinpoint one explanation. They cite many contributing factors, ranging from professional training groups that have sprouted across the United States to greater access to underwater cameras and other advanced technology.

But some say the most significant breakthrough has been a revival of a swimming maneuver developed more than 70 years ago by one of the physicists who worked on the atomic bomb.

Though utilized for decades, the underwater dolphin kick had not been fully exploited by the swimming mainstream until Olympic megastar Michael Phelps and a few other stars began polishing it — and crushing other swimmers with it — in recent years.

The underwater dolphin kick attracted the interest of swimming innovators as early as the 1930s. The late Volney C. Wilson explored its possibilities before diving into later work on nuclear fission and the atomic bomb, according to David Schrader, a research professor at Marquette University who is Wilson’s biographer.

Schrader said Wilson, an alternate on the 1932 Olympic water polo team who studied fish propulsion at a Chicago aquarium, claimed to have shown the kick to Johnny Weissmuller, a training mate at the Illinois Athletic Club. “Weissmuller reproduced it perfectly, but was not impressed by it,” said Schrader in a phone interview, recalling a conversation with Wilson.
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One of the first swimmers to turn heads with the underwater dolphin kick was David Berkoff, a Harvard graduate who became known for the “Berkoff Blastoff.” In 1988, Berkoff set several world records in the 100 backstroke by dolphin-kicking for 35 meters underwater at the start of the race.

David Acheson is the nation’s top food detective, but so far he has met his match in the wily tomato.

With the salmonella scare that has plagued tomatoes, Acheson has faced perhaps his biggest test—at least as far as outbreaks of illness go—since he assumed the newly created “food safety czar” post at the U.S. Food and Drug Administration about a year ago.

That position was born amid a growing concern that the FDA couldn’t get a grip on food safety, as tales of food-borne illnesses multiplied. Now comes salmonella-laden tomatoes that have sickened at least 277 people nationwide, hospitalizing 43.
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The FDA concluded that the tainted tomatoes most likely came from Mexico or a certain part of Florida. The agency managed to narrow down the possible origins of the tainted tomatoes largely by a process of elimination. Based on the timing of their growing seasons and tomato harvests, many states or countries could not be the source of the tomatoes that caused illnesses, so they were deemed safe sources.

Restaurants and food retailers say they are now sourcing tomatoes from places deemed safe by the FDA. The outbreak has been a particularly tough one to crack because it has been so widespread. Illness has shown up in people who frequented a variety of restaurants, and who bought tomatoes at myriad grocery stores.

And when we look at the wealth of opportunities hovering on the horizon — stem cells, genomic sequencing, personalized medicine, longevity research, nanoscience, brain-machine interface, quantum computers, space technology — we realize how crucial it is to cultivate a general public that can engage with scientific issues; there’s simply no other way that as a society we will be prepared to make informed decisions on a range of issues that will shape the future.

These are the standard - and enormously important - reasons many would give in explaining why science matters.

But here’s the thing. The reason science really matters runs deeper still. Science is a way of life. Science is a perspective. Science is the process that takes us from confusion to understanding in a manner that’s precise, predictive and reliable - a transformation, for those lucky enough to experience it, that is empowering and emotional. To be able to think through and grasp explanations - for everything from why the sky is blue to how life formed on earth - not because they are declared dogma but rather because they reveal patterns confirmed by experiment and observation, is one of the most precious of human experiences.

Daniel Burd’s project won the top prize at the Canada-Wide Science Fair in Ottawa. He came back with a long list of awards, including a $10,000 prize, a $20,000 scholarship, and recognition that he has found a practical way to help the environment.
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First, he ground plastic bags into a powder. Next, he used ordinary household chemicals, yeast and tap water to create a solution that would encourage microbe growth. To that, he added the plastic powder and dirt. Then the solution sat in a shaker at 30 degrees.

After three months of upping the concentration of plastic-eating microbes, Burd filtered out the remaining plastic powder and put his bacterial culture into three flasks with strips of plastic cut from grocery bags. As a control, he also added plastic to flasks containing boiled and therefore dead bacterial culture.

Six weeks later, he weighed the strips of plastic. The control strips were the same. But the ones that had been in the live bacterial culture weighed an average of 17 per cent less.
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The inputs are cheap, maintaining the required temperature takes little energy because microbes produce heat as they work, and the only outputs are water and tiny levels of carbon dioxide — each microbe produces only 0.01 per cent of its own infinitesimal weight in carbon dioxide, said Burd.

“This is a huge, huge step forward . . . We’re using nature to solve a man-made problem.” Burd would like to take his project further and see it be used. He plans to study science at university, but in the meantime he’s busy with things such as student council, sports and music.