This Roadmap is a call to action that provides a vision for atomically precise manufacturing technologies and productive nanosystems. The United States nanotechnology advancement goal should be to lead the world towards the development of these revolutionary technologies in order to improve the human condition by addressing grand challenges in energy, health care, and other fields. The United States can accomplish this goal through accelerated global collaborations focused on two strategies that will offer ongoing and increasing benefits as the
technology base advances:

1. Develop atomically precise technologies that provide clean energy supplies and a cost-effective energy infrastructure.
2. Develop atomically precise technologies that produce new nanomedicines and multifunctional in vivo and in vitro therapeutic and diagnostic devices to improve human health.
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Close cooperation among scientific and engineering disciplines will be necessary because of the nature of the engineering problems involved. This cross-disciplinary collaboration will bring broad benefits through the cross-fertilization of ideas, instruments, and techniques that will result from developing the required technology base.

With international cooperation, the benefits of productive nanosystems will be delivered to the world faster. Coordinating a full international
effort is extremely desirable in order to minimize duplication of effort in smaller national programs conducted independently.