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General education related posts. Sub-categories include primary and secondary education, higher education and scholarships and fellowships.
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Roominate: Inspiring Artists, Engineers and Visionaries

Roominate is a cool new toy created by 3 engineering students aimed at giving young engineers a way to learn, experiment and create. The 3 women used kickstarter to get the funds needed to launch their product. They raised $85,000 (the goal was $25,000).

We’re more than just a toy company. We want to inspire your daughters to be the great artists, engineers, architects, and visionaries of their generation. We intend to give them every tool to reach that potential.

Founders:

Bettina Chen: CalTech BS in Electrical Engineering, masters in Electrical Engineering from Stanford.

Alice Brooks: MIT BS in Mechanical Engineering, currently at Stanford pursuing masters in Mechanical Engineering design.

Jennifer Kessler: Bachelor degree from University of Pennsylvania, currently an MBA student at Stanford.

This is yet another example of entrepreneurship shown by Standford students. The USA is hugely benefited by Stanford (along with a few other schools: MIT, Caltech, etc.). There is little a country can do that is as helpful economically as encouraging the type of entrepreneurship Standford does.

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Great Webcast Explaining the Digestive Systems

You will learn things like why it is so important to chew your food well (increase the surface area for enzymes to get at the food). Our bodies also have adapted to provide a huge surface area for the digestive system to work; the small intestine alone has a surface area of 250 square meters (larger than the size of most apartments). Your small intestine is 4.5 to 10.5 meters long.

Related: Staphylococcal Food PoisoningEnergy Efficiency of DigestionTracking the Ecosystem Within UsWaste from Gut Bacteria Helps Host Control Weight

Virus Kills Breast Cancer Cells in Laboratory

Some very exciting and good news from Penn State. Researchers have found a virus that kills breast cancer cells. It is great to read about research breakthroughs like this. Of course, most of these announcements never become practical solutions, unfortunately. And if they do it is many many years later and almost always in much less exciting ways than the headlines. Still, the percentage that do make it through the process into workable solutions provide us great benefits.

Virus kills breast cancer cells in laboratory

Adeno-associated virus type 2 (AAV2) is a virus that regularly infects humans but causes no disease. Past studies by the same researchers show that it promotes tumor cell death in cervical cancer cells infected with human papillomavirus. Researchers used an unaltered, naturally occurring version of AAV2 on human breast cancer cells.

“Breast cancer is the most prevalent cancer in the world and is the leading cause of cancer-related death in women,” said Samina Alam, research associate in microbiology and immunology. “It is also complex to treat.”

“We can see the virus is killing the cancer cells, but how is it doing it?” Alam said. “If we can determine which viral genes are being used, we may be able to introduce those genes into a therapeutic. If we can determine which pathways the virus is triggering, we can then screen new drugs that target those pathways. Or we may simply be able to use the virus itself.”

AAV2 does not affect healthy cells. However, if AAV2 were used in humans, the potential exists that the body’s immune system would fight to remove it from the body. Therefore, by learning how AAV2 targets the death pathways, researchers potentially can find ways to treat the cancer without using the actual virus.

In ongoing studies, the Penn State researchers also have shown AAV2 can kill cells derived from prostate cancer, mesothelioma, squamous cell carcinoma, and melanoma. A fourth line of breast cancer cells — representing the most aggressive form of the disease — also was studied in a mouse breast tumor model, followed by treatment with AAV2. Preliminary results show the destruction of the tumors in the mice, and researchers will report the findings of those mouse studies soon.

The fight against cancer has many promising breakthroughs. We have made some great progress. Still the fight is extremely difficult and we have many more frustrations than successes.

Related: Webcast of a T-cell Killing a Cancerous CellSynthetic Biologists Design a Gene that Forces Cancer Cells to Commit SuicideResearchers Find Switch That Allows Cancer Cells to Spread

Physical Activity for Adults: Inactivity Leads to 5.3 Million Early Deaths a Year

Obviously health care doesn’t only mean sickness treatment. Avoiding sickness is much better than treating it. Sadly we spend far too little energy on creating health and far too much on treating sickness.

Physical activity guidelines for adults (follow link for more details and guidelines for others) from the UK National Health Service

To stay healthy, adults aged 19-64 should try to be active daily and should do:

  • At least 150 minutes (2 hours and 30 minutes) of moderate-intensity aerobic activity such as cycling or fast walking every week, or
  • 75 minutes (1 hour and 15 minutes) of vigorous-intensity aerobic activity such as running or a game of singles tennis every week
  • and muscle-strengthening activities on 2 or more days a week that work all major muscle groups (legs, hips, back, abdomen, chest, shoulders and arms).

Sedentary lifestyle can kill

one in three adults worldwide fails to do the recommended 150 minutes of moderate aerobic physical activity per week. In the UK two out of three adults don’t manage it.

So rather than stressing the health benefits of exercise, the Lancet researchers have opted to show the harm caused by inactivity. They estimate lack of exercise is responsible for about 5.3m deaths a year – about the same number as smoking.

This is based on estimates of the impact on inactivity on coronary heart disease, Type 2 diabetes, and two specfic cancers – breast and bowel – where lack of exercise is a major risk factor.

Related: Today, Most Deaths Caused by Lifetime of InactionStudy Finds Obesity as Teen as Deadly as SmokingCan Just A Few Minutes of Exercise a Day Prevent Diabetes?An Apple a Day is Good Advice

Effect of physical inactivity on major non-communicable diseases worldwide: an analysis of burden of disease and life expectancy

Worldwide, we estimate that physical inactivity causes 6% (ranging from 3·2% in southeast Asia to 7·8% in the eastern Mediterranean region) of the burden of disease from coronary heart disease, 7% (3·9—9·6) of type 2 diabetes, 10% (5·6—14·1) of breast cancer, and 10% (5·7—13·8) of colon cancer. Inactivity causes 9% (range 5·1—12·5) of premature mortality, or more than 5·3 million of the 57 million deaths that occurred worldwide in 2008. If inactivity were not eliminated, but decreased instead by 10% or 25%, more than 533 000 and more than 1·3 million deaths, respectively, could be averted every year. We estimated that elimination of physical inactivity would increase the life expectancy of the world’s population by 0·68 (range 0·41—0·95) years.

High School Student Creates: Test That is Much More Accurate and 26,000 Times Cheaper Than Existing Pancreatic Cancer Tests

Seeing what these kids come up with is so refreshing after being so disappointed by the actions fo our leaders (politicians, business leaders, financiers, law enforcement [spying on citizens because they feel electronic privacy is fine to invade, taking away liberty...], health care in the USA [twice as expensive as elsewhere with no better results, 10 of millions without coverage]…). These kids make me feel hopeful, unfortunately the actions of the powerful leave me less hopeful.

Jack Andraka created a new paper based test for diagnosing pancreatic cancer that is 50% more accurate, 400 times more sensitive, and 26,000 times less expensive than existing methods. His method uses carbon nanotubes and can catch the disease in very early stages which is critical to treatment success. The test also covers other forms of cancer very effectively (he concentrated on the results for pancreatic cancer given the low survival rates for that cancer). Jack Andraka: “I actually love single-walled carbon nanotubes; they’re like the superheroes of material science.”

His results are great. Often initial results can be difficult to actually turn into such positive results in the real world. But this is a great step and it is great to see what young minds can do. The claims for how much better, cheaper etc. are wildly different in various places on the International Science and Engineering Fair (ISEF) site.

Jack Andraka was awarded $75,000 for his development of a new method to detect pancreatic cancer as the winner of the top prize at the Intel ISEF (I believe it is new this year to call the winner the Gordon E. Moore Award).

Related: 2009 Intel Science and Engineering Fair WebcastsIntel International Science and Engineering Fair 2007Intel Science Talent Search 2012 AwardeesGoogle Science Fair 2011 Projects

A Novel Paper Sensor for the Detection of Pancreatic Cancer by Jack Andraka
North County High School, Glen Burnie, MD

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Citizen Science: Use Your Smart Phone to Help Scientists

10 Ways You Can Use Your Smartphone to Advance Science by Matt Soniak

Scientists have started to use the abilities and prevalence of smartphones to their advantage, creating apps specifically for their studies and crowdsourcing observation and data collection. When almost everyone has an Internet connection, a camera, and a GPS unit right in their phone, almost anyone can gather, organize, and submit data to help move a study along.

The Indicator Bats Program (iBats), a joint project of the Zoological Society of London’s Institute of Zoology and The Bat Conservation Trust, got its start with a couple of researchers working in Transylvania (of course) in 2006. The idea of the project is to identify and monitor bat populations around the world by the ultrasonic echo-location calls they use to navigate and find prey.

The goal of Project NOAH (Networked Organisms and Habitats) is pretty ambitious: “build the go-to platform for documenting all the world’s organisms.” Their app has two modes. “Spottings” lets you take photos of plants and animals you see, categorize and describe them and then submit the data for viewing on NOAH’s website and use by researchers for population and distribution studies.

Invasive plants and animals can crowd out natives, compete with them for food sources and alter the fire ecology of an ecosystem, disrupting its natural balance. Researchers and programmers from UCLA, the Santa Monica Mountains National Recreation Area and the University of Georgia have teamed up to create the What’s Invasive citizen science program and smartphone app. Volunteers can use the app to look up lists of the top invasive species in their area, created by National Park Service rangers and biologists. If they spot a plant or animal from the list, they submit a geo-tagged observation, with optional picture and text notes, so that scientists can locate, identify, study try to remove the species.

Great stuff.

Related: Backyard Scientists Aid ResearchCellphone MicroscopeThe Great Sunflower Project

Science PhD Job Market in 2012

The too-big-to-fail-bank crisis continues to produce huge economic pain throughout the economy. Science PhDs are not immune, though they are faring much better than others.

U.S. pushes for more scientists, but the jobs aren’t there

Since 2000, U.S. drug firms have slashed 300,000 jobs, according to an analysis by consulting firm Challenger, Gray & Christmas. In the latest closure, Roche last month announced it is shuttering its storied Nutley, N.J., campus — where Valium was invented — and shedding another 1,000 research jobs.

Largely because of drug industry cuts, the unemployment rate among chemists now stands at its highest mark in 40 years, at 4.6 percent, according to the American Chemical Society, which has 164,000 members. For young chemists, the picture is much worse. Just 38 percent of new PhD chemists were employed in 2011, according to a recent ACS survey.

Two groups seem to be doing better than other scientists: physicists and physicians. The unemployment rate among those two groups hovers around 1 to 2 percent, according to surveys from NSF and other groups. Physicists end up working in many technical fields — and some go to Wall Street — while the demand for doctors continues to climb as the U.S. population grows and ages.

But for the much larger pool of biologists and chemists, “It’s a particularly difficult time right now,” Stephan said.

From 1998 to 2003, the budget of the National Institutes of Health doubled to $30 billion per year. That boost — much of which flows to universities — drew in new, young scientists. The number of new PhDs in the medical and life sciences boomed, nearly doubling from 2003 to 2007, according to the NSF.

The current overall USA unemployment rate is 8.2%.

The current economy doesn’t provide for nearly guaranteed success. The 1960′s, in the USA, might have come close; but that was a very rare situation where the richest country ever was at the prime of economic might (and even added on top of that science was seen as key to promote continued economic success). Today, like everyone else (except trust fund babies), scientists and engineers have to make their way in the difficult economy: and that should be expected to be the case in the coming decades.

Right now, physicians continue to do very well but the huge problems in the USA health system (we pay double what other rich countries do for not better outcomes) make that a far from a certain career. They likely will continue to do very well, financially, just not as well as they have been used to.

Science and engineering education prepare people well for economic success but it is not sufficient to guarantee the easy life. Just like everyone else, the ability to adapt to current market conditions is important in the current economic climate – and will likely continue to be hugely important going forward.

The reason to get a undergraduate or graduate science or engineering education is because you are interested in science and engineering. The economic prospects are likely to continue to be above average (compared to other education choices) but those choosing this path should do so because they are interested. It makes sense to me to factor in how your economic prospects will be influenced by your choices but no matter what choices are made a career is going to take hard work and likely many frustrations and obstacles. But hopefully a career will provide much more joy than hardship.

Related: Career Prospect for Engineers Continues to Look PositiveAnother Survey Shows Engineering Degree Results in the Highest PayThe Software Developer Labor Market

Special Summer Fun Issue of Make Magazine

Make is really is a wonderful way to find ideas. Some people have the imagination to come up with all sorts of projects to try, I don’t. But Make takes care of that for you and provides really interesting ideas for things to try out yourself.

The summer fun guide includes over 50 projects for kids of all ages.

Related: Book on Adventures in MakingAwesome Gifts for the Maker in Your LifeThe DIY Movement Revives Learning by Doing

Today, Most Deaths Caused by Lifetime of Action or Inaction

Chart of the Leading Causes of Death in 1900 and 2010

Our instincts lead us to fear the unknown and immediate threats (probably so we can be ready to run – or maybe fight). But today the biggest risks to an untimely dealt are not lions, other people out to get us, or even just random infection. We have to adapt to the new risks by taking action to eat healthfully and exercise, in the same way we we have evolved to avoid becoming a meal for a hungry beast.

Today the largest causes of death are heart disease and cancer (which account for more than 60% of the deaths causes by the top 10 leading causes of death). The next leading causes are non-infectious airways diseases, cerebrovascular diseases and accidents. Alzheimer’s, diabetes, nephropathies, pneumonia or influenza and suicide make of the rest of the top 10 leading causes.

In 1900 Pneumonia or influenza and tuberculosis took as many lives (per 100,000 people) and cancer and heart disease take today. We have done well decreasing the incidents of death (fewer deaths per 100,000) by greatly reducing and nearly eliminating some causes of death (the 2 leading causes from 1900 are good examples).

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Good Chemistry: A Love Song for Ionic Bonds

Song and video by 10th grade student, Eli Cirino, for extra credit in his chemistry class.

An ionic bond is a type of chemical bond formed through an electrostatic attraction between two oppositely charged ions. Ionic bonds are formed between a cation, which is usually a metal, and an anion, which is usually a nonmetal.

An ionic bond is considered a bond where the ionic character is greater than the covalent character (ionic bonds cannot exist on their own, they must have a covalent bond present also).

Related: Protein Synthesis: 1971 VideoCooking with Chemistry: Hard CandyThe Chemistry of Hair Coloring

Teen Solves Puzzle That Has Stumped Mathematicians for 300 Years

Teen solves Newton’s 300-year-old riddle

An Indian-born teenager has won a research award for solving a mathematical problem first posed by Sir Isaac Newton more than 300 years ago that has baffled mathematicians ever since.

The solution devised by Shouryya Ray, 16, makes it possible to calculate exactly the path of a projectile under gravity and subject to air resistance. Shouryya, who lives in Dresden, eastern Germany, came up with the solutions to this and a second mathematical riddle while working on a school project.

Only partial solutions had been discovered up to now, requiring simplified assumptions or calculations by computer. Shouryya’s elegant solutions could contribute to greater precision in fields such as ballistics.

Related: Teen Tackles Centuries-old Numbers challenge (this time it was an Iraqi immigrant in Sweden)Numeracy: The Educational Gift That Keeps on GivingOur Brains Reorganize As We Learn Math

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