Category Archives: Health Care

Sexy Math

Mean Girls:

British researchers, stated that men had 12.7 heterosexual partners in their lifetimes and women had 6.5.” These numbers, though Kolata doesn’t say so, are means, not medians. In this case, it’s indeed mathematically impossible that the numbers are correct. The medians in the British sample? Seven and four, same as in the American study—so you can stop worrying about a transatlantic promiscuity gap.
“It is logically impossible for heterosexual men to have more partners on average than heterosexual women,” she explains. “Those survey results cannot be correct.” Kolata even quotes a theorem to this effect, backed up by mathematician David Gale of Berkeley: The average number of partners has to be the same for men and women.

This article makes several good mathematical and scientific points, including the dangers of trusting reports by participants. Also I can see if this page is more popular than some of the other math posts. For awhile now I have noticed “sex 100” showing up as one of the terms guiding the most visitors to this site. I wondered what that could be – I just took a look: Bdelloid Rotifers Abandoned Sex 100 Million Years Ago. I think maybe those searchers didn’t exactly find what they wanted.

Regular Aerobic Exercise for a Faster Brain

Lobes of Steel

Scientists have suspected for decades that exercise, particularly regular aerobic exercise, can affect the brain. But they could only speculate as to how. Now an expanding body of research shows that exercise can improve the performance of the brain by boosting memory and cognitive processing speed. Exercise can, in fact, create a stronger, faster brain.

But something else happened as a result of all those workouts: blood flowed at a much higher volume to a part of the brain responsible for neurogenesis. Functional M.R.I.’s showed that a portion of each person’s hippocampus received almost twice the blood volume as it did before. Scientists suspect that the blood pumping into that part of the brain was helping to produce fresh neurons.

The hippocampus plays a large role in how mammals create and process memories; it also plays a role in cognition. If your hippocampus is damaged, you most likely have trouble learning facts and forming new memories. Age plays a factor, too. As you get older, your brain gets smaller, and one of the areas most prone to this shrinkage is the hippocampus. (This can start depressingly early, in your 30’s.) Many neurologists believe that the loss of neurons in the hippocampus may be a primary cause of the cognitive decay associated with aging.

Related: Feed your Newborn NeuronsCan Brain Exercises Prevent Mental Decline?Excercize and LearningNo Sleep, No New Brain Cells

Common Virus May Contribute to Obesity

Common virus may contribute to obesity

Infection with human adenovirus-36 (Ad-36) seems to direct adult stem cells from fat tissue to turn into fat cells, researchers have found in lab experiments. Stem cells not exposed to the virus, in contrast, were unchanged. More importantly, the researchers have identified the specific gene in the virus that appears to be involved in this obesity-promoting effect: E4Orfl.

The field of research investigating the role of viruses in obesity — dubbed “infectobesity” — is still relatively new and experimental. Researchers don’t believe that infection with one of these pathogens is the sole cause of obesity but they say some obesity cases may involve viral infections.

Related: Eat food. Not too much. Mostly plants.Obesity Epidemic Explained$500 Million to Reduce Childhood Obesity in USAWhy Most Published Research Findings Are False

Raised Without Antibiotics

Tyson is going to start selling chicken Raised Without Antibiotics. The overuse of antibiotics is a huge problem and the overuse in the raising of livestock is a huge problem.

“While we have great confidence in the quality of our traditional chicken, we’re also committed to providing mainstream consumers with the kind of products they want,” said Richard L. Bond, president and CEO of Tyson Foods. “According to our research, 91% of consumers agree it’s important to have fresh chicken produced and labeled ‘raised without antibiotics’,” Bond said.

Tyson started selling 100% All Naturalâ„¢, Raised Without Antibiotics chicken this week. The product is being distributed nationwide in newly-designed packaging highlighting that the chicken is raised without antibiotics and contains no artificial ingredients.

While it is nice they will start selling a portion of chicken raised without using antibiotics and endangering the health of the community by helping evolve super-resistant bugs this is really a pretty small step I would guess. The risk is not even mainly to the person eating the food pumped full of antibiotics it is to everyone when drug resistant bacteria are evolved through the overuse of antibiotics. Also, 100% All Natural is trademarked? Give me a break.

Nationwide Survey Reveals Most Americans are Unaware They Consume Beef and Poultry Raised on Antibiotics (2003)

“Antibiotic medicines are losing effectiveness on humans due to their increased use in animal feed,” said Margaret Mellon, Ph.D, JD, director of the food and environment program for the Union of Concerned Scientists. “Animals raised in natural environments rarely require the use of antibiotics. Americans who choose meat produced this way are making conscious decisions to ensure that antibiotics will still be working when they or their family need them.” The Union of Concerned Scientists estimates that 70 percent of all antibiotics in the United States are now fed to animals raised for human consumption in order to hasten the animals’ growth or prevent illness amid crowded, unsanitary conditions on factory farms.

Abuse of Antibiotics at Factory Farms Threatens the Effectiveness of Drugs Used to Treat Disease in Humans:

According to the Center for Disease Control, more than one-third of the salmonella poisoning cases in 1997 were found to be resistant to five antibiotics. Drug resistance in campylobacter bacteria, the most commonly known cause of bacterial food-borne illness in the United States, increased from zero in 1991 to 14 percent in 1998.

The European Union, on the recommendation of the World Health Organization, has banned the use of antibiotics to promote the growth of livestock animals when those drugs are also used to treat people. The Center for Disease Control has agreed with this position, but the U.S. government has failed to reduce the threat that ineffective antibiotics pose to human health. (Lieberman, et.al., 1999)

To reduce serious health threats, the Food and Drug Administration should ban the use of antibiotics to promote livestock growth when those antibiotics are used to treat humans.

Over-reliance on Prescription Drugs to Aid Children’s Sleep?

Waiting for the sandman

In the report, published in the Aug. 1 issue of the journal Sleep, researchers at Ohio State University in Columbus analyzed 18.6 million reported cases of sleep disorders in patients age 17 and younger. They found that 81 percent of these cases resulted in the prescribing of a drug to treat the problem. Only 7 percent of patients received dietary counseling, and only 22 percent were given behavioral therapies such as psychotherapy or stress management counseling.

Along with the perception (which I share) that we look to pills to fix problems too often (and the belief that drugs have risks and should not be overused) this is not good news.

He adds that it’s very reasonable for doctors to prescribe a sleep aid for a short time, to smooth the transition while behavioral changes are made. Behavioral approaches are almost always worth trying, he says: “It’s very easy to develop some disorders, and it can be very easy to get rid of them as well.”

However, only 19 percent of cases in the study received medication in concert with behavior therapy. Chervin adds that in some cases, such as when a child is developmentally impaired, behavioral approaches may not be appropriate.

But there are other factors at work, experts say. Pediatricians may be too busy, or influenced by parents not to try behavioral approaches, which can be time-intensive. Oftentimes, says Dr. William Kohler, medical director of the Florida Sleep Institute, “if we don’t use [medication], both the family and the child are going to suffer.”

Related: Antibiotics Too Often Prescribed for Sinus WoesEpidemic of DiagnosesOveruse of AntibioticsFlushed Drugs Pollute Water

Contradictory Medical Studies

I have written before about false research findings. This is an important topic – we need to remember that the interpritation of one study (or many studies) in not necessarily conclusive. Another article – When Medical Studies Collide:

Two years ago, the headlines blared that echinacea was a bust. Millions of people who believed the best-selling herbal remedy was warding off colds were probably deluding themselves, according to The New England Journal of Medicine. Now echinacea is back in the news. This time, it works! So says a study in The Lancet Infectious Diseases.

How could two studies come to such different conclusions—especially when there have been no new trials of the herb? While the New England Journal reported on one clinical trial, authors of the latest report combined data from previous studies, a controversial approach called a meta-analysis. Its conclusion is dramatically different—not just from that of the New England Journal paper, but also from a review last year of the same studies.

The problem is, the world of medical and health research is messier than most people realize. Black-and-white answers are rare, even when it comes to a single drug trial.

Just remember those last two sentences. Very simple. And most people would agree if you showed them those two sentences and asked if they agreed. But then they see a headline and away they go… Just force yourself to repeat that idea every time you see a health report. Don’t believe the headline without strong support.

An interesting tidbit from the article. The coneflower is the source of echinacea. I tried to find photos that I am pretty sure I have on my hard drive of the flowers in my back yard, but I couldn’t.

Related: Correlation is Not CausationAnother Paper Questions Scientific Paper Accuracy

Research on Why Healthy Living Leads to Longer Life

New Clue into How Diet and Exercise Enhance Longevity

In their experiments, the researchers sought to understand the role of the insulin-like signaling pathway in extending lifespan. This pathway governs growth and metabolic processes in cells throughout the body. The pathway is activated when insulin and insulin-like growth factor-1 switch on proteins inside the cell called insulin receptor substrates (Irs).

Other researchers had shown that reducing the activity of the pathway in roundworms and fruitflies extends lifespan. Despite those tantalizing clues, White said, “The idea that insulin reduces lifespan is difficult to reconcile with decades of clinical practice and scientific investigation to treat diabetes.” “In fact, based on our work on one of the insulin receptor substrates, Irs2, in liver and pancreatic beta cells, we thought more Irs2 would be good for you,” said White. “It reduces the amount of insulin needed in the body to control blood glucose, and it promotes growth, survival and insulin secretion from pancreatic beta cells.

“Diet, exercise and lower weight keep your peripheral tissues sensitive to insulin. That reduces the amount and duration of insulin secretion needed to keep your glucose under control when you eat. Therefore, the brain is exposed to less insulin. Since insulin turns on Irs2 in the brain, that means lower Irs2 activity, which we’ve linked to longer lifespan in the mouse.”

Related: Eat food. Not too much. Mostly plants.Regular Exercise Reduces FatigueDiabetes Breakthrough$500 Million Over the Next 5 Years to Help Reduce Childhood Obesity in USA

Lifestyle Drugs and Risk

I see taking drugs as risky. Certain drug have long histories and seem safe and even seem to have positive side effect like Aspirin (though even it is not without risks – see below). Even if a drug has a good chance of a positive result in treating some medical condition – assuming it is otherwise safe is not wise. I believe you have have a significant positive known benefit to consider taking drugs given the unknown problems that are likely to be lurking. I find the pop a pill culture for anything that might be a minor annoyance to be foolish – taking risks without consideration. Taking drugs entails taking a risk and the more you take the risks of interactions and cumulative effects increase the risks to you. Business Week (somewhat surprising given the huge amount drug makers pay to advertise lifestyle drugs) has a decent article pointing out some of the foolishness involved in the Lifestyle Drug Binge:

The renewed excitement is most evident in four treatment areas that account for the bulk of lifestyle-drug sales: weight loss, hair loss, sleep, and sexual dysfunction.

This trend is surprising because such treatments can expose patients to risks, sparking criticism of drug companies at a time when patient safety is already under a spotlight. Lifestyle drugs are defined loosely as products used to treat conditions that are not life-threatening. Because people take them over long periods of time, sometimes on a daily basis, they may be more dangerous than they first appear.

We have found amazingly helpful and useful drugs. This is great. But people need to remember these drugs are not without potential negative consequences. Take advantage of them when appropriate but don’t forget the risks each instance has for negative side effects. Related: health care improvement articleshealth care blog posts
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Obesity Epidemic Explained – Kind Of

chart showing obesity by country

Graphic: percentage of population over 15 with a body-mass index greater than 30, for more see Wellington Grey

Obesity Epidemic Explained – Kind Of

So maybe everyone else already knew this and I am like, bumpkin girl, but I just have to take a moment and point everyone to this USDA research site on the massive inflationary trend in daily caloric consumption over the past three decades.

1970 – Americans ate an average of 2170 calories per day
2000 – Americans ate an average of 2700 calories per day

I don’t think most people know that. It does seem odd to me that so much effort is put into trying to come up with explanations that are much more complicated. Most of the complicated suggestions (usually some explanation that indicates it is some biology issue and not eating to much or exercising too little) don’t explain why there is an increase in the incidence of obesity over time – at least I don’t see how they do. It seems to me the base requirement for improving the health issue of increasing obesity is to have an explanation of what has caused the incredible increase.

I can certainly believe biological issues impact how easy it is to become obese or how difficult it is to maintain a healthy weight. But it seems to me the proportion of the population that is obese has drastically increased over time (or different regions of the globe with a similar genetic makeup) and the logical place to look for an explanation is behavior differences that created this change (not some biological issue that has changed). If 5% of the population was predisposed obesity in 1950 to obesity I can’t see any rational reason to think that has increased to 30% today.

Related: Eat food. Not too much. Mostly plants.CDC on ObesityChemicals May Play Role in Rise in ObesityDrinking Soda and ObesityTreadmill Desks$500 Million to Reduce Childhood Obesity in USAFood Health Policy Blog
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Chocolate Every Day Will Keep the Doctor Away

We need more news like this: A Bite of Chocolate a Day May Keep Blood Pressure at Bay:

Chocolate lovers can rejoice again: More research has found that the antioxidants in dark chocolate can help slightly lower blood pressure. But the good news comes with a caveat — the chocolate portions have to be limited to 30 calories a day, which works out to slightly more than one Hershey’s Kiss.

Such small amounts of the flavanol-rich cocoa found in dark chocolate “may be a promising behavioral approach to lower blood pressure in individuals with above-optimal blood pressure,” the German researchers reported in their study. Unlimited quantities of chocolate won’t work, they added, because “the potential blood pressure reduction contributed by the flavanols could be offset by the high sugar, fat and calorie intake with the cocoa products.”

Ok, I’ll admit I am eating a bit more than that but I have cut back my Mountain Dew from 2 day a couple years ago to maybe 3 a week now so I figure I have some leeway 🙂 Remember it has to be the dark chocolate with flavanol – given the recent positive press those the packaging usually makes the point of mentioning that the good stuff is included if it is.

Related: Eat food. Not too much. Mostly plantsAnother Strike Against ColaDrinking Soda and ObesityEat Less Salt and Save Your Heart