Medical Study Results Questioned

Third of study results don’t hold up (cnn broke the link so I removed it);

in a review of major studies published in three influential medical journals between 1990 and 2003, including 45 highly publicized studies that initially claimed a drug or other treatment worked.

Subsequent research contradicted results of seven studies — 16 percent — and reported weaker results for seven others, an additional 16 percent.

The scientific community will gain once the barriers to the flow of knowledge created by subscription sites. We would link to the actual study but it is not available – it is behind a subscription wall. Support the adoption of the Public Library of Science and the Public Library of Medicine.

The Mysteries of Mass

The Mysteries of Mass (bozos at Scientific American broke the page so I removed the link – poor usability):

Physicists are hunting for an elusive particle that would reveal the presence of a new kind of field that permeates all of reality. Finding that Higgs field will give us a more complete understanding about how the universe works.

Autonomous Vehicle Technology Competition

DARPA Grand Challenge:

The Defense Advanced Research Projects Agency (DARPA) today announced the 40 teams selected to advance to the semifinals of the DARPA Grand Challenge 2005 autonomous ground vehicle competition. The teams come from 14 states and Canada and represent varied backgrounds including universities, individuals, corporations, and a high school.
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The team that develops an autonomous ground vehicle that finishes the designated route most quickly within 10 hours will receive $2 million.

Only if a team succeeds will the the money be paid. Last year no team succeeded.

The Future of Scholarly Publication

Scholarly journals’ premier status diluted by Web by Bernard Wysocki Jr., The Wall Street Journal:

In the U.S. a powerful open-access advocate has been Harold Varmus, a Nobel laureate, former UC scholar and former NIH director. He’s now head of Memorial Sloan Kettering Cancer Center in New York. He co-founded Public Library of Science with Berkeley’s Dr. Eisen, backed by a $9 million grant from a private foundation. Charging authors a fee of $1,500, the group launched its first peer-reviewed journal, PLoS Biology, in 2003, and also distributes its contents free on the Internet.

I have nothing against Journals trying to stay in business. I do however, think the internet has created a better method of distributing information than existed previously. And, given the current state of the internet, I do object to scientific knowledge being kept out of the scientific and public community. The ability to use the internet to more effectively communicate new knowledge should not be sacrificed to protect the old model journals had for sustaining themselves. They should find a way to fund themselves and make their material availalbe for free on the internet (I think some delay for free public access would be fine – the shorter the delay the better). Or they should be replaced by others that do so.

Luckily sites like the Public Library of Science (freely accessible online scholarly publications) are offering such an alternative.

Six-legged Intestinal Robot

Robot combined with swallowable camera could give docs a better look inside the small intestine by Byron Spice, Pittsburgh Post-Gazette:

Metin Sitti, director of the NanoRobotics Lab, is developing a set of legs that could be incorporated into the swallowable camera-in-a-pill that has become available in the past four years for diagnosing gastrointestinal disorders in the small intestine.
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The work is supported by the Intelligent Microsystems Center in Seoul, Korea, and sponsored by the Korean Ministry of Commerce, Industry and Energy.
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Another CMU roboticist, Cameron Riviere, is developing his own robotic inchworm that would use suction pads to adhere to the exterior of a beating heart. The two-footed device, called HeartLander, might be used to inject cells or drugs, implant electrodes or perform coronary artery bypass procedures.

Metin Sitti is an engineer with Carnegie Mellon University.

Nano Printing

New technique may speed DNA analysis:

In the new printing method, called Supramolecular Nano-Stamping (SuNS), single strands of DNA essentially self-assemble upon a surface to duplicate a nano-scale pattern made of their complementary DNA strands. The duplicates are identical to the master and can thus be used as masters themselves. This increases print output exponentially while enabling the reproduction of very complex nano-scale patterns.

Even Tech Execs Can’t Get Kids to Be Engineers

Even Tech Execs Can’t Get Kids to Be Engineers by Ann Grimes:

Silicon Valley is doing a lot of hand-wringing these days about a coming engineer shortage. Tech leaders such as Cisco Systems Inc.’s John Chambers and Stanford University President John Hennessey warn that the U.S. will lose its edge without homegrown talent. The U.S. now ranks 17th world-wide in the number of undergraduate engineers and natural scientists it produces, they point out; that’s down from 1975, when the U.S. was No. 3 (after Japan and Finland).

But some of the nation’s tech elite — including many immigrants who benefited greatly from engineering careers — are finding even their own children shun engineering. One oft-cited reason: concern that dad and his contemporaries will ship such jobs overseas.

Appropriate Technology

Technology is not only about new breakthroughs. In some cases the technology used is nothing special, the impact is made in applying the technology well. Many opportunities exist for breakthroughs using technology that has been around for a long time.

I was reminded of my father‘s work by the article: From Stanford Engineering to Social Innovation (broken link):

In 1991, Martin Fisher and Nick Moon founded ApproTEC, a non-profit organization that develops technologies for alleviating poverty. More than 36,000 farmers in Kenya have now used their low-cost water pumps to create their own small businesses. They hope to take 400,000 people out of poverty in the next few years.

From the ApproTEC web site (broken link – it sure gets annoying how many people fail to follow basic web usability guidelines such as keeping links alive – organization now called KickStart):

ApproTEC’s Impacts To Date
Over:
  • 35,000 new businesses started * 800 new businesses per month
  • $35 million a year in new profits and wages generated by the new businesses
  • New incomes account for over 0.5% of Kenya’s GDP and 0.2% of Tanzania’s GDP

On a related note, TrickleUp is my favorite charity. Their mission: to help the lowest income people worldwide take the first steps up out of poverty, by providing conditional seed capital, business training and relevant support services essential to the launch or expansion of a microenterprise.

John Hunter

Nanoscience’s Master Mechanic

Nanoscience’s Master Mechanic by David Pescovitz (from the University of California – Berkeley’s excellent Science Matters Newsletter):

The Center of Integrated Nanomechanical Systems (COINS) aims to develop a storehouse of mechanical components hundreds of times smaller than the diameter of a human hair.
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“Right now, we make most nanodevices one at a time, sometimes as laboriously as atom by atom,” Zettl says. “That approach can prove a concept, but if you can’t scale up then it becomes a curiosity instead of a viable technology. We need automated assembly at the nanoscale.”