Author Archives: curiouscat

River Blindness Worm Develops Resistance to Drugs

Resistance could lead to breakouts of the infection in communities where it has been brought under control, a Canadian study in the Lancet reports. Ivermectin, used since the late 1980s, is the only drug available for the mass treatment of river blindness. Experts warned the findings highlighted the urgent need for new treatments. River blindness (onchocerciasis) is caused by a nematode worm which is transmitted by a black fly.
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He added that isolated resistance could be controlled by using insecticides or an antibiotic called doxycycline, which is effective but needs to be given every day for a long time.
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Professor Taylor’s team have recently received a large grant from the Bill and Melinda Gates Foundation to search for new drugs or combinations that can have the same effect as a course of doxycycline but delivered in shorter time frame.

The Bill and Melinda Gates Foundation is funding a tremendous amount of important work.

Education, Entrepreneurship and Immigration

Education, Entrepreneurship and Immigration: America’s New Immigrant Entrepreneurs is part 2 of a study by Duke’s Pratt School of Engineering and UC Berkeley. Some interesting points from the study:

52 percent of immigrant founders initially came to the United States primarily for higher education, 40 percent entered the country because of a job opportunity, 6 percent came for family reasons, and only 2 percent to start a business.
91 percent of Indian founders, 35 percent of Chinese and 97 percent of Taiwanese founders completed their undergraduate degrees in their home country
Indian and Chinese founders graduated from a diverse set of schools in their native countries, many of which are considered
second- or third-tier universities (only 15 percent of Indian founders were graduates of the IIT).
Immigrant founders of technology and engineering firms have strong backgrounds in science, technology, engineering, and mathematics (STEM) fields. 75 percent had completed their highest degree in a STEM field.
Advanced education in science, technology, engineering, and mathematics is correlated with high rates of entrepreneurship and innovation. The U.S. economy depends upon these high rates of entrepreneurship and innovation to maintain its global edge.

High Resolution Darwin Documents

View high resolution scans of Darwin’s notes and review his thoughts and ideas. Speaking of Faith (American Public Media program) has teamed with Cambridge University Library to present a narrated tour of Darwin’s private notebooks and hand sketches with David Kohn.

Very interesting. I am not thrilled with the usability of the web application but the high resolution images are interesting and the narration is informative.

Singapore Students Engineer New Products

Students design products to help environment and disabled people

“Now it’s in the eighth year and we’ve had 5,000 students on the scheme. This year the quality is quite good, I’m quite happy. Some amazing ideas such as the fish scaling device and the shuttlecock launcher,” said Mr Butler. There is no limit to innovation and creativity.

An automated shuttlecock launcher, which can adjust the launching angle of shuttlecocks, came in tops in terms of design. Currently there are no mechanical shuttlecock launchers in the market. But this launcher can not only be produced at a low cost, but also help beginners execute different strokes. Another practical design is a retractable bamboo system that improves safety when drying laundry. It also comes with a plastic cover to keep out the rain. The above are just a few examples of the 52 innovations that may just find their way into our homes and lives, once these young technopreneurs find the right investors.

I like the increasing efforts to engage university students in actually creating useful innovations. It isn’t easy to actually create winning solutions but the efforts to do so I think teach many valuable lessons. Such efforts support a change to our education system to engaging students in actual engineering projects not just problem sets (for example: Educating the Engineer of 2020: NAE Report – Olin Engineering Education Experiment – Changes at MIT for Engineering Education – Educating Engineering Geeks).

Self Healing Plastic

Plastic That Heals Itself

The first self-healing material was reported by the UIUC [University of Illinois at Urbana-Champaign] researchers six years ago, and other research groups have created different versions of such materials since then, including polymers that mend themselves repeatedly when subject to heat or pressure. But this is the first time anyone has made a material that can repair itself multiple times without any external intervention, says Nancy Sottos, materials-science and engineering professor at UIUC and one of the researchers who led the work.
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the researchers bend it and crack the polymer coating. The crack spreads down through the coating and reaches the underlying microchannel. This prompts the healing agent to “whip through the channels and into the crack,” Sottos says. There, it comes into contact with the catalyst and, in about 10 hours, becomes a polymer and fills in the crack. The system does not need any external pressure to push the healing agent into the crack. Instead, the liquid moves through the narrow channels just as water moves up a straw.

Order Your CatCam

You can now order your CatCam (or components to help put together your own) from Juergen Perthold the creator of the wonderful CatCam as we posted last week: Awesome CatCam. Very cool.

Boston Travel Photos

After I presented the Deming Seminar in Boston last year a spent a few extra days in to enjoy the city. See photos from my Boston visit including: Boston Science Museum (above photo), Boston Fine Arts Museum and Boston Common.

Life-patents

New Life, New Patent by Carl Zimmer:

ETC is right in suggesting Venter might become “Microbesoft”–controlling operating system for anyone who wants to build an organism from scratch. Other researchers, such as Keasling, are promoting a different way of doing synthetic biology–what they call open source biology. Scientists and their students are amassing an open inventory of parts that anyone can use to design organisms of their own. And it’s open source biology, these researchers argue, that will provide the best protection against any evil uses of synthetic biology. Instead of being hidden behind patents, the information about these parts would be available to everyone, and collectively solutions could be found. As this debate starts to unfold, I think open source biology will keep it from becoming nothing but deja vu.

I support keeping science open. Patents are a tax on society that the government grants inventors for their efforts, in order to benefit society, by encouraging the inventors to innovate. The end is benefiting society. The means is granting a right of the patent holder (a right they do not have without patent law) that will encourage them to make the effort to innovate. I support the proper use of patents, but we have perverted the patent process into something that harms society. The system needs to be fixed. And the whole area of patents on life I find very questionable.

Antibacterial Products May Do More Harm Than Good

photo of a dandelion

Strange but True: Antibacterial Products May Do More Harm Than Good by Coco Ballantyne:

Unlike these traditional cleaners, antibacterial products leave surface residues, creating conditions that may foster the development of resistant bacteria, Levy notes. For example, after spraying and wiping an antibacterial cleaner over a kitchen counter, active chemicals linger behind and continue to kill bacteria, but not necessarily all of them.

When a bacterial population is placed under a stressor—such as an antibacterial chemical—a small subpopulation armed with special defense mechanisms can develop. These lineages survive and reproduce as their weaker relatives perish. “What doesn’t kill you makes you stronger” is the governing maxim here, as antibacterial chemicals select for bacteria that endure their presence.

Pretty basic understanding of evolution makes the breeding of very resilient bacteria a fairly obvious result. One thing that might not be as obvious until it is mentioned is that by killing off the “weaker” bacteria you also provide a niche for the more resilient bacteria to multiply and fill the gap left by the bacteria that were not a problem that were killed off. Imagine if, instead of digging out the 3 dandelions you wanted to remove from your yard, you removed all plants from your yard (including those 3 dandelions). I would bet most often that would result in more dandelions not fewer as the dandelions were able to fill in the void of plants in the yard.

In general, however, good, long-term hygiene means using regular soaps rather than new, antibacterial ones, experts say. “The main way to keep from getting sick,” Gustafson says, “is to wash your hands three times a day and don’t touch mucous membranes.”

National Underwater Robotics Challenge

See the National Underwater Robotics Challenge web site for information on the event in Arizona June 8th through 10th. They offer a remote underwater vehicle kit for $250.

The ROV-IN-A-BOX is intended to help get teams involved that are new to underwater robotics. Buy purchasing this kit, it helps put an inexperienced team, or a team with young students like elementary school kids, into a comfort zone to allow them to take on the Underwater Challenge. It reduces the stress, time and resources needed to acquire all the parts to complete an ROV for the competition. The kit can also be used by a more mature team as a starting point for the ROV they may want to build.

There will be a live video stream June 9 at 8pm MST and will continue to until about 2am MST June 10. The video will come from both the ROV and in the pool with event cameras in and around the submarine. Once the video has been processed and mixed poolside by Arizona State University’s Applied Learning Technologies Institute, it will then be channeled to Chandler High School’s television studio, where it will be broadcast to a view gallery and simultaneously sent to a server at ASU where it will be webcast to the world.

Video of the ROV in a box:
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