When Shivani Sud was six years old, one of her immediate family members was diagnosed with a brain tumor. Inspired by the doctors who helped her loved one recover, Shivani set her sights on a career in medicine.

Fast forward to Intel STS 2008, where the 17-year-old senior from Durham, North Carolina, presented research focused on identifying stage II colon cancer patients at high risk for recurrence and the best therapeutic agents for treating their tumors. Whereas the standard method of characterizing tumors relies on visual information (such as size, degree
of metastasis, and microscopic structure), Shivani developed a “50-gene model” which uses gene expression to link multiple genetic events that characterize various tumor types to more accurately predict the recurrence of colon cancer. Additionally, Shivani’s model can be used to identify drugs that may be most effective in treating each patient.