Posts about innovation

Using Bacteria to Power Microscopic Machines

Scientists at the U.S. Department of Energy’s (DOE) Argonne National Laboratory and Northwestern University have discovered that common bacteria can turn microgears when suspended in a solution, providing insights for designs of bio-inspired dynamically adaptive materials for energy.

“The ability to harness and control the power of bacterial motion is an important requirement for further development of hybrid biomechanical systems driven by microorganisms,” said Argonne physicist and principal investigator Igor Aronson. “In this system, the gears are a million times more massive than the bacteria.”

A few hundred bacteria work together in order to turn the gear. When multiple gears are placed in the solution with the spokes connected as in a clock, the bacteria will turn both gears in opposite directions, causing the gears to rotate in synchrony—even for long stretches of time.

“There exists a wide gap between man-made hard materials and living tissues; biological materials, unlike steel or plastics, are ‘alive,’” Aronson said. “Our discovery demonstrates how microscopic swimming agents, such as bacteria or man-made nanorobots, in combination with hard materials, can constitute a ‘smart material’ which can dynamically alter its microstructures, repair damage, or power microdevices.”

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IBM Fellow Grady Booch on the Value of Engineering?

In this webcast IBM Fellow Grady Booch discusses the critical role engineering plays in moving society forward. And he explores the history of science and engineering. This interesting webcast would be a good video to show children, or anyone, to bring out the desire to study engineering and encourage them to study so they can join the many engineers shaping our world and our future.

Related: What is an Engineer?Engineer Tried to Save His Sister and Invented a Breakthrough Medical DeviceThe Engineer That Made Your Cat a PhotographerEngineers Should Follow Their Hearts

Innovation, America and Engineering: NAE Grand Challenges Summit

Innovation, America and Engineering: NAE Grand Challenges Summit in Raleigh, North Carolina:

Friday morning in Raleigh, a group of engineers from industry, academia and even government met to discuss the threat of America losing its global lead in innovation. The panel discussion was part of a Summit on the National Academy of Engineering Grand Challenges

Jeff Wadsworth, CEO and president of Battelle Memorial Institute, noted that high school graduation rates have fallen from about 86 percent in the Baby Boomer generation to about 72 percent today. He compared that to a 96 percent graduation rate in Denmark, 92 percent in Japan and the fact that China graduates three engineering students for every one that we do. It’s not news that international competition is stiffening against us, but the statistics he presented about how the U.S. measures up to foreign countries in K-12 metrics was gut-wrenching.

“Our historic lead in secondary education has disappeared,” Wadsworth said. “And as a leader of a large organization, I worry about education.”

Another panelist, Senator Ted Kaufman (D-Delaware) said the country was at a critical point in history. “We are in an economic war,” he said. “The future of our country rests on our ability to use STEM to solve problems.” Kauffman is the only sitting senator in Congress to have worked in the engineering field, and he repeatedly drummed out a message that policy could drive a solution to the STEM crisis.

A third panelist – John Chambers, chairman and CEO of CISCO – said he believed changing teaching methods in K-12 settings to be more collaborative, projects-oriented and skills-mastery oriented would be a good starting point.

the deans of the engineering colleges at both Duke and NC State universities announced today a new nationwide program targeting attracting school-aged children to the STEM fields. The Grand Challenge K-12 Partners Program will lean on engineering colleges throughout the U.S. to be resource hubs for K-12 students and teachers in their region.

Three more NAE Grand Challenge Summits are scheduled to take place next month, in Phoenix, Chicago and Boston. A fourth is scheduled for Seattle in May.

The importance of innovation and engineering education to long term economic success is one thing I believe strongly in and have written about here: Engineering Economic Benefits, Techonolgy Innovation Global Economy Changing, Centers of Technical Excellence and Economic Power. And is one reason I work for the American Society of Engineering Education (this blog is my own and not associated with ASEE).

Related: USA Losing Scientists and Engineers Educated in the USAInvest in Science for a Strong Economy

Apple’s iPad

Steve Jobs introduces the Apple iPad. A touch screen tablet with wireless internet connectivity and a touch screen keyboard (when desired).

Related: Freeware Wi-Fi app turns iPod into a PhoneLow-Cost Multi-touch Whiteboard Using Wii RemoteBuild Your Own Tabletop Interactive Multi-touch ComputerVery Cool Wearable Computing Gadget from MIT

Siftable Modular Computers

Pretty cool. I must admit I don’t really see how this would function outside of specifically designed situation. I can imagine it could be very cool for education, especially of young kids. Siftables act in concert to form a single interface: users physically manipulate them – piling, grouping, sorting – to interact with digital information and media. David Merrill and Jeevan Kalanithi originally created Siftables at the MIT Media Lab and have formed a company to commercialize the product and have received a grant from NSF to continue the work.

Related: Cool Mechanical Simulation SystemVideo Cat CamArduino: Open Source Programmable HardwareWhat Kids can Learn

Printing Bone, Muscle and More

A Pittsburgh-based research team has created and used an innovative ink-jet system to print “bio-ink” patterns that direct muscle-derived stem cells from adult mice to differentiate into both muscle cells and bone cells.

The custom-built ink-jet printer, developed at Carnegie Mellon’s Robotics Institute, can deposit and immobilize growth factors in virtually any design, pattern or concentration, laying down patterns on native extracellular matrix-coated slides (such as fibrin). These slides are then placed in culture dishes and topped with muscle-derived stem cells (MDSCs). Based on pattern, dose or factor printed by the ink-jet, the MDSCs can be directed to differentiate down various cell-fate differentiation pathways (e.g. bone- or muscle-like).

“This system provides an unprecedented means to engineer replacement tissues derived from muscle stem cells,” said Johnny Huard, professor of orthopedic surgery at the University of Pittsburgh School of Medicine and director of the Stem Cell Research Center at Children’s Hospital of UPMC. Huard has long-standing research findings that show how muscle-derived stem cells (MDSCs) from mice can repair muscle in a model for Duchenne Muscular Dystrophy, improve cardiac function following heart failure, and heal large bone and articular cartilage defects.

Weiss and Campbell, along with graduate student Eric Miller, previously demonstrated the use of ink-jet printing to pattern growth factor “bio-inks” to control cell fates. For their current research, they teamed with Phillippi, Huard and biologists of the Stem Cell Research Center at Children’s Hospital to gain experience in using growth factors to control differentiation in populations of MDSCs from mice.

The team envisions the ink-jet technology as potentially useful for engineering stem cell-based therapies for repairing defects where multiple tissues are involved, such as joints where bone, tendon, cartilage and muscle interface. Patients afflicted with conditions like osteoarthritis might benefit from these therapies, which incorporate the needs of multiple tissues and may improve post-treatment clinical outcomes.

The long-term promise of this new technology could be the tailoring of tissue-engineered regenerative therapies. In preparation for preclinical studies, the Pittsburgh researchers are combining the versatile ink-jet system with advanced real-time live cell image analysis developed at the Robotics Institute and Molecular Biosensor and Imaging Center to further understand how stem cells differentiate into bone, muscle and other cell types.

Related: Engineer Tried to Save His Sister and Invented a Breakthrough Medical DeviceNanoparticles With Scorpion Venom Slow Cancer SpreadVery Cool Wearable Computing Gadget from MITFunding Medical Research

Engineering a Better Football

The football (soccer ball) for the 2010 FIFA World Cup features completely new, ground-breaking technology. Eight 3-D spherically formed panels are moulded together, harmoniously enveloping the inner carcass. The result is an energetic unit combined with perfect roundness.

Aero grooves create the clearly visible profile on the ball’s surface. The Grip’n'Groove profile circles around the entire ball in an optimal aerodynamic way. The integrated grooves provide unmatched flight characteristics, making this the most stable and most accurate Adidas football. The ground breaking performance features have been confirmed in comprehensive comparison tests at Loughborough University in England and countless checks in wind tunnel and the Adidas football laboratory in Scheinfeld, Germany.

The process, shown in the video, for manufacturing the footballs is way more complicate than I thought it would be.

Related: Full Adidas press releaseThe Science of the Football SwerveEngineering Basketball FlopSports Engineering

Bionic Vision

Micro Machines and Opto-Electronics on a Contact Lense

Fiction now meets reality with prototype contact lenses developed by Babak Parviz at the University of Washington, in Seattle. Dr. Parviz’s prototype lenses can be used as biosensors to display body chemistry or as a heads up display (HUD). Powered by radio waves and 330 microwatts of power from a loop antenna that picks up power beamed from nearby radio sources, future versions will also be able to harvest power from a cell phone.

In his early 2008 lab tests, rabbits safely wore contact lenses with metal connectors for electronic circuits. The prototype lenses contained an electric circuit as well as red light-emitting diodes for a display. The lenses were tested on rabbits for up to 20 minutes and the animals showed no adverse effects.

Contact lenses as replacements for smart phone displays — even to monitor blood glucose levels — might best be done while not operating heavy equipment. “The true promise of this research is not just the actual system we end up making, whether it’s a display, a biosensor, or both,” comments Dr. Parviz. “We already see a future in which the humble contact lens becomes a real platform, like the iPhone is today, with lots of developers contributing their ideas and inventions. As far as we’re concerned, the possibilities extend as far as the eye can see, and beyond.”

Related: A Journey Into the Human Eye3-D Images of EyesScientists Discover How Our Eyes Focus When We Read

Teenage Engineer’s Company Launches Safety Stair

Young engineer launches stair aid by Geoff Adams-Spink

A young woman from Sheffield has turned a GCSE coursework project into an award-winning stair-climbing device for older and disabled people. Ruth Amos has launched her StairSteady handrail at Naidex 2008 – the annual disability exhibition in Birmingham.

She told BBC News that she was inspired to create the device for the father of one of her teachers who had had a stroke. She won an award for her idea and has now set up a company to sell it. The StairSteady is a horizontal rail at 90 degrees to the wall or banister that people can hold on to as they go up or down stairs.

The invention was then entered for the Young Engineer for Britain competition and won first prize.

Great stuff. Innovation doesn’t have to be amazing technology. Finding solutions that make people’s lives better is the key. And then showing some entrepreneurship is great, Ruth setup her company when she was 16. I wish her luck.

Related: posts on engineersEngineers Should Follow Their HeartsAutomatic Dog Washing MachineEntrepreneurial and Innovative EngineersMicrofinancing Entrepreneurs

Engineering: Cellphone Microscope

UCLA Professor Aydogan Ozcan‘s invention (LUCAS) enables rapid counting and imaging of cells without using any lenses even within a working cell phone device. He placed cells directly on the imaging sensor of a cell phone. The imaging sensor captures a holographic image of the cells containing more information than a conventional microscope. The CelloPhone received a Wireless Innovations Award from Vodafone

a wireless health monitoring technology that runs on a regular cell-phone would significantly impact the global fight against infectious diseases in resource poor settings such as in Africa, parts of India, South-East Asia and South America.

The CelloPhone Project aims to develop a transformative solution to these global challenges by providing a revolutionary optical imaging platform that will be used to specifically analyze bodily fluids within a regular cell phone. Through wide-spread use of this innovative technology, the health care services in the developing countries will significantly be improved making a real impact in the life quality and life expectancy of millions.

For most bio-medical imaging applications, directly seeing the structure of the object is of paramount importance. This conventional way of thinking has been the driving motivation for the last few decades to build better microscopes with more powerful lenses or other advanced imaging apparatus. However, for imaging and monitoring of discrete particles such as cells or bacteria, there is a much better way of imaging that relies on detection of their shadow signatures. Technically, the shadow of a micro-object can be thought as a hologram that is based on interference of diffracted beams interacting with each cell. Quite contrary to the dark shadows that we are used to seeing in the macro-world (such as our own shadow on the wall), micro-scale shadows (or transmission holograms) contain an extremely rich source of quantified information regarding the spatial features of the micro-object of interest.

By making use of this new way of thinking, unlike conventional lens based imaging approaches, LUCAS does not utilize any lenses, microscope-objectives or other bulk optical components, and it can immediately monitor an ultra-large field of view by detecting the holographic shadow of cells or bacteria of interest on a chip. The holographic diffraction pattern of each cell, when imaged under special conditions, is extremely rich in terms of spatial information related to the state of the cell or bacteria. Through advanced signal processing tools that are running at a central computer station, the unique texture of these cell/bacteria holograms will enable highly specific and accurate medical diagnostics to be performed even in resource poor settings by utilizing the existing wireless networks.

This is another great example of engineers creating technologically appropriate solutions.

Related: Better health through your cell phoneMobile Phone-based Vehicle Anti-theft SystemAppropriate Technology: Self Adjusting GlassesEngineering a Better World: Bike Corn-ShellerThe Engineer That Made Your Cat a PhotographerFreeware Wi-Fi app turns iPod into a Phone

Researching Direct Brain Interfaces for Text Entry

Adam Wilson posted a status update on the social networking Web site Twitter — just by thinking about it. A UW-Madison biomedical engineering doctoral student, Wilson is among a growing group of researchers worldwide who aim to perfect a communication system for users whose bodies do not work, but whose brains function normally. Among those are people who have amyotrophic lateral sclerosis (ALS), brain-stem stroke or high spinal cord injury.

The interface consists, essentially, of a keyboard displayed on a computer screen. “The way this works is that all the letters come up, and each one of them flashes individually,” says Williams. “And what your brain does is, if you’re looking at the ‘R’ on the screen and all the other letters are flashing, nothing happens. But when the ‘R’ flashes, your brain says, ‘Hey, wait a minute. Something’s different about what I was just paying attention to.’ And you see a momentary change in brain activity.”

The system still is not very quick. However, as with texting, users improve as they practice using the interface. “I’ve seen people do up to eight characters per minute,” says Wilson.

Read full press release

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